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Efficacy of adjuvant mitotane treatment in prolonging recurrence -free survival in -patients with adrenocortical carcinoma at low-intermediate risk of recurrence

Primary objectiveTo compare the efficacy of adjuvant mitotane treatment vs observational follow-up only in prolonging recurrence free survival (RFS) in patients with ACC after complete resection and low-intermediate risk for disease recurrence.…

Towards cost-effective diagnostic management of patients with primary aldosteronism: adrenal vein sampling or CT-scan?

Here we propose to perform a prospective, randomized, multicenter study that compares effectiveness of AVS with effectiveness of CT-scanning for the diagnosis of PA subtype. There is no criterion standard for accuracy of the diagnosis of PA-subtype…

Diagnostic value of 11C-metomidate Positron Emission Tomography/Computerized Tomography (PET/CT) for the evaluation of primary aldosteronism: a pilot study

The objective of the study is to determine whether 11C-metomidate PET can differentiate between BAH and APA./PAH

Quality of life, cognitive functioning, psychopathology, and personality traits in patients with primary adrenal insufficiency

To answer the following research questions:How is quality of life in patients with adrenal insufficiency?How is cognitive functioning in patients with adrenal insufficiency?Is there a difference in cognitive functioning between patients who did/did…

Salivary cortisol in children with asthma and/or rhinitis: effect of topical steroids and correlation with symptoms and lungfunction

Evaluate the effect of topical steroids on salivary cortisol levels, and assess the correlation between salivary cortisol levels, symptoms of asthma, and lungfunction in children with asthma and/or rhinitis

Consequences of suboptimal glucocorticoid replacement therapy in Addison*s disease; The metabolic syndrome and quality of life.

Assess the prevalence of the metabolic syndrome and quality of life in patients with Addison*s disease treated with low dose GRT. Study the relation between GRT, QoL and glucocorticoid receptor polymorphisms

Effect of standardized running test on salivary cortisol respons in prepubertal children

To evaluate if a standardized running test will elicit an increase in salivary cortisol levels in healthy prepubertal children

Pheochromocytoma randomised study comparing adrenoreceptor Inhibiting
agents for preoperative treatment (PRESCRIPT)

The primary objective is to determine which of two commonly used drugs for preoperative management provides the best intraoperative hemodynamic control in patients undergoing resection of a PCC. Secondary Objective(s): o to identify other…