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A multicenter prospective study of biochemical profiles of monoamine-producing tumors: utility
for diagnosis and determinants of clinical presentation. (The PMT study)

Primary objective:to identify new and improved disease biomarkers and establish the biochemical and molecular basis for variations in the clinical presentation of the different groups of tumors.Secondary objectives:• compare the diagnostic utility…

Pharmacokinetic modeling of mitotane

The main objective of this study is to construct a population-pharmacokinetic model, in order to evaluate the influence of patient characteristics on the pharmacokinetics of mitotane in patients treated with this oral therapy.