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Optimizing timing of glucocorticoid treatment in children with congenital adrenal hyperplasia

To study the effects of 2 standard treatment timing strategies for glucocorticoid dosage on androgen concentration in CAH children: a. highest dosage in the morning, b. highest dosage in the evening.

The stress hormone COrtisol and the development of MEtabolic Syndrome and Cardiovascular DIseases
Unravelling the cause(s) of hypercortisolism in obesity:
Investigating the influence of the liver, gut and immune system

Primary Objective: - To investigate the differences between hypercortisolistic patients with obesity and normocortisolistic patients with obesity, with respect to hepatic steatosis, immunological factors, and the gut microbioma in order to obtain…