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A Multicenter Single-arm Extension Study to Describe the Long-term Efficacy and Safety of AMG 416 in the Treatment of Secondary Hyperparathyroidism in Subjects With Chronic Kidney Disease on Hemodialysis

Primary Objective: To characterize the long-term safety and tolerability of AMG 416 in the treatment of SHPT in subjects with CKD on hemodialysisSecondary Objective: To characterize the long-term efficacy of AMG 416 on intact parathyroid hormone (…

Assessment of Bone Quality by Microindentation in Patients with Bone Diseases

1. To explore the validity and usefulness of Bone Microindentation Technique (BMT) in the assessment of bone quality in patients with osteoporosis and a spectre of bone diseases characterised with (localised) increased bone turnover. 2. To study the…

Coagulation and fibrinolysis in hyperparathyroidism secondary to Vitamin D Deficiency: the CoViDD study

Aim of our study is to investigate the influence of HPT secondary to moderate-severe vitamin D deficiency and vitamin D replacement on the coagulation and fibrinolysis system