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The influence of metformin and a hypocaloric diet on thyroid radioactive iodide uptake in healthy volunteers: a pilot study.

To assess the physiological effects of metformin and hypocaloric dieting on thyroid iodide uptake and thyroid function in healthy volunteers.

Mutations in thyroid hormone receptor alpha 2

The family with the TRα2 premature stop enables us to investigate the biological role of the orphan wild-type TRα2 and the consequences of its dysfunction. The primary objectives of this proposal are (i) to search for a biological function of TRα2…

Fast-track thyroidectomy and radioiodine ablation therapy in patients with differentiated thyroid cancer.

This study aims to detect differences in sick leave time, associated costs and quality of life between differentiated thyroid cancer patients treated in either a fast-track protocol or a traditional longer time interval between total thyroidectomy…

Cognitive and motor development, nerve function, somatic growth and (pubertal) development, and (spontaneous) thyroid function in 10,5 years old Down syndrome children after thyroxine or placebo treatment until the age of 2 years.

To find out whether T4 treatment of Down syndrome newborns until the age of 2 years compared with placebo treatment results in better cognitive or motor development at the age of 10 years and 6-8 months, and whether it is safe with regard to nerve…

Determinants and mediating mechanisms of quality of life and disease-specific symptoms among thyroid cancer patients: the WaTCh study

Our main objective is to assess QoL and disease-specific symptoms over time. Our secondary objectives are to identify demographic, environmental, biological, physiological and personality characteristics of TC patients who are at high risk for poor…