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A national randomized placebo-controlled double-blind multicenter trial of
LT4/LT3 combination therapy in patients with autoimmune
hypothyroidism.

This study has been transitioned to CTIS with ID 2024-513883-24-00 check the CTIS register for the current data. Primary Objective: To investigate the effects of LT4/LT3 combination therapy compared to LT4 monotherapy on tiredness in those patients…

Medical assessment of adverse health outcomes in Dutch childhood cancer survivors; a nationwide project; SKION LATER Q2008 onderzoek:
Thyroid function, in children and adults, after treatment for childhood cancer

To assess the prevalence of hypothyroidism and hyperthyroidism in the entire cohort of childhood cancer survivors and the therapy related risk factors. Specifically:Part I: 1. To systematically review existing studies on the association between…

The sensitivity of the pituitary thyrotrophs for ambient thyroid hormone levels.

The aim of this pilot study is;* To determine whether differences between individuals in the set-point of the HPT-axis can be determined by using this study-design,* To examine whether this study design is practicable and tolerated by the healthy…

Explaining the Down syndrome specific thyroid phenotype by epigenetics

To provide further evidence for the role of long-term epigenetic effects of an extra chromosome 21 on HPT-axis associated genes as an explanation of DS associated thyroid phenotype, in a series of DS individuals in whom data on thyroid functioning…