20 results
To further optimize 7.0 Tesla MRI techniques and to develop new MRI techniques that will enable state-of-the-art clinical and cognitive research leading to improved patient care. Whereas some applications of 7.0 Tesla MRI already show improvements…
The primary goal of our study is to map and characterize anatomically and functionally the subcortical structures of the auditory pathway in patients with tinnitus and compare them to controls. To this end, we will use 7 T MRI scanner and measure…
The objective of this study is to examine the vestibular system in three dimensions. To achieve this goal three experiments are performed. The EyeSeeCam video-oculography is validated with the scleral search coils (international golden standard).…
to measure neural activity of the central nervous system in tinnitus related brain areas in cochlear implant recipients with chronic tinnitus and to determine the relation between this neural activity and the subjective tinnitus experience of…
To gain information about the characteristics of the oVEMP response in patients with BRIC type 1
The objective of he study is to develop and evaluate a dynamic visual acuity test, with an added value over the conventional static visual acuity test. We hope that this test can eventually be used as a (military) selection tool and as a test that…
Primary objective: to investigate the prevalence of vestibulotoxicity and disturbance of equilibrium as far a Cystic Fibrosis patients with at least one treatment with tobramycin are concerned. Secondary objective: To formulate an advice for…
The main objective is to demonstrate the activation of the efferent inhibitory cortico-olivocochlear pathway with otoacoustic emission of the ear contralateral to the side of stimulation with TMS. We expect the amplitude to decrease after TMS of the…
The primary objective of this study is to objectivate neural hyperactivity at the cortical level of chronic tinnitus sufferers compared to control subjects with the use of FDG-PET-scans.
The primary objective is to clarify the frequency of t-BPPV in patients after mild TBI. Secondary objectives are: assessment of the symptoms of t-BPPV and the treatment success of t-BPPV.
The main objective of the study is to better explain disappointing speech recognition in individual cases, with as ultimate goal to find optimal individual settings for the sound processor (outside the scope of this project). We test two new methods…
To determine the sensitivity and specificity of the HINTS+ test in detecting a central cause in patients with acute onset, continuous dizziness in a general ED population, when performed by general neurologists/ED physicians.
The aim of this study is to measure eCAPs intraoperatively (and perform electrocochleography [ECochG] in case of any residual hearing) and to estimate cochlear health in these patients by applying insights gained from our guinea pig experiments.
This study has been transitioned to CTIS with ID 2024-512860-75-00 check the CTIS register for the current data. The aim of this feasibility study is to validate pre-treatment [89Zr]-bevacizumab PET/CT as an imaging biomarker for prediction of…
Primary aimTo determine the prevalence of children with hearing loss at time of discontinuation of cancer therapy in a prospective full cohort of 600 children with solid and CNS tumors.The secondary objectives of this study are:- To study the…
Primary Objectives: • To evaluate the subjective and objective cognitive complaints and cognitive function in patients receiving radiotherapy for their vestibular schwannoma. Secondary objectives:• To explore the use of (MRI) imaging biomarkers for…
We aim that by assessing listening effort subjectively with an adaptive categorical listening effort scale (ACALES) we can demonstrate the possibly increased listening effort in tinnitus patients.
To validate the method of measuring torsional eye movementsTo measure 3D eye movementsTo assess the age dependency of the responsesTo measure the gain of eye- versus headmovement and retinal slip velocity in clinical diagnosis by comparing patients…
The aim of this observational and exploratory study is to describe the accuracy of gaze stabilization in the presence of abnormal vestibular and visual functions. Visually induced image movements are used as the basis for gaze stability for each…
To report the natural history of retinal degeneration in patients with biallelic mutations in the USH2A gene; to identify sensitive structural and functional outcome measures to use for future multicenter clinical trials in USH2A-related retinal…