163 results
The primary objective of this clinical trial is to demonstrate the safety and effectiveness of the Combo Bio-engineered Sirolimus Eluting Stent (Combo Stent) compared to the commercially available TAXUS® Liberté® Paclitaxel-Eluting Stent (DES) in…
The purpose of the study is to compare the combination of DEB/BMS versus DES versus BMS alone in patients with an AMI.
To demonstrate the arrhythmogenic action of MSG in a single blinded placebo controlled test on these patients with reported MSG induced AF and to investigate the possibility of MSG as a potential trigger for AF.
The main objective of the study is a head tot head comparison of the everolimus coated XIENCE-V* stent with the paclitaxel coated TAXUS* stent in order to observe whether there is a difference in clinical outcome between both stents. Efficacy of…
The objective of the ABSORB PHYSIOLOGY is to evaluate the following in participants undergoing coronary artery scaffolding/stenting for significant coronary artery disease:• The acute (post-implantation) effect of an implanted BVS or mDES on…
The primary aim of the trial is to assess what the optimal treatment regimen for acetylsalicylic acid, a statin and two BP-lowering agents is (administered as in regular care in individual agents, a fixed-dose combination pill administered in the…
The aim of the study is to evaluate the effect of warm blood cardioplegia administration without rollerpump on perioperative myocardial injury in patients undergoing coronary artery bypass grafting (CABG) with a minimal extracorporeal circuit (MECC…
Objective of this study is to determine (1) whether mindfulness training has an additional clinical and psychological effect to standard care, and (2) whether offering mindfulness training is a cost-effective intervention, in adult patients with…
The main objective of the present study is to investigate whether the ORSIRO coronary stent is non-inferior compared to the Xience coronary stent in patients with total coronary occlusions.
· Explore the relative impacts of iodine concentration versus iodine delivery rate on intra-coronary attenuation. · Describe the effect of iodine concentration on contrast bolus characteristics e.g. bolus homogeneity, time-to-peak, and pressure…
The trial will test the hypothesis that ICD implantation without defibrillation testing (DT) is non-inferior to implantation with testing against the composite endpoint of ineffective first appropriate clinical shock or arrhythmic death.
Does a low protamine-to-heparin ratio lead to a reduction in postoperative blood loss and improved postoperative hemostasis when compared to a high protamine-to-heparin ratio in cardiothoracic surgery?
To evaluate the safety and effectiveness of the STENTYS Coronary Stent System in the treatment of de novo stenotic lesions in coronary arteries in subjects undergoing primary revascularization due to Acute ST Segment Elevation Myocardial Infarction…
NOACs have no need for regular monitoring, this could have an effect on adherence. It is our objective to study adherence and patient satisfaction in WIPPS guided and non-WIPPS guided patients using Rivaroxaban
The intent of this study is to evaluate the safety and efficacy of the implanted Accent MRI system, which includes the investigational St. Jude Medical Tendril MRI* lead and Accent MRI* pacemaker, in the MRI environment. An MRI Activator* will be…
The main objective of the study is to investigate whether HIT after CRT results in an additional increase in maximal exercise capacity. Secondary objectives are to investigate whether HIT yields additional improvements in submaximal exercise…
To demonstrate the safety and effectiveness of the Tryton Side Branch Stent* with main branch approved DES compared to side branch balloon angioplasty and main branch approved DES in the treatment of de novo native coronary artery bifurcation…
To demonstrate non-inferiority in terms of neointimal coverage of Cre8 (CID) Drug Eluting Stent, evaluated at three months afterstent implantation, compared to Vision/Multilink 8 (Abbott) Bare Metal Stent evaluated at one month, in terms of…
To identify the influence of two different biocompatible-coated extracorporeal circuits on the perfused boundary region of the sublingual microvasculature as measured by the GlycoCheck Sidestream Darkfield Imaging camera.
To determine if HF subjects whose treatment is assisted by a daily BNP measurement that is integrated into a home health management system will have improved clinical outcomes versus subjects whose treatment includes home health management but is…