412 results
Primary Objective: To compare the effects of hypothyroidism and hyperthyroidism on cardiac left ventricular function, as assessed by CMR, in subjects with differentiated thyroid cancer during their early treatment.Secondary Objective(s): To compare…
Primary Objective • To assess the effects of 80mg of furosemide delivered by subcutaneous delivery in the abdominal area over 5 hours when compared to oral administration in patients with heart failure with chronic fluid overload. Secondary…
To investigate whether circadian rhythms in patients with chronic systolic heart failure are disturbed
The overall purpose of the study is to determine the effectiveness of structured introduction and access to a Wii game computer in patients with heart failure (HF) to improve their exercise capacity, their daily physical activity, decrease health…
Main objective: To investigate whether spironolactone can favourably alter extra-cellular matrix remodelling, assessed by changes in the fibrosis biomarker Procollagen Type III N-Terminal Peptide (PIIINP), in patients at increased risk of developing…
The primary objective of this study is:to evaluate the effect of RPM + in-clinic follow-up versus in-clinic follow-up only on patient-reported health status/quality of life after implantation with an ICD/CRT-D device. The secondary objectives are: 1…
To demonstrate the efficacy of AdreView* imaging for appropriately guiding the decision of ICD implantation in a population of New York Heart Association (NYHA) class II and III Heart Failure (HF) patients with 25% * left ventricular ejection…
1) To study the late effects of 131-I treatment and TSH suppressive therapy as well as quality of life in patients with childhood-onset DTC. 2) To determine the presence of RET/PTC 1 and 3 translocations and BRAF mutations, and to investigate their…
The aim of this study is to evaluate the effects of treatment on the exertional contractile reserve and RV-arterial coupling during exercise in CTEPH patients. Furthermore, we evaluate the effects on the exertional contractile reserve and RV-…
The aim of this project is (1) to examine reproducibility of measuring CO and LBF with PC-MRI during supine cycling (phase I) and (2) to measure CO and LBF during supine cycling in patients with CHF and healthy age-matched controls to investigate…
The primary objective of this study is to identify in which imaging modality, including CE and vortex imaging, could help us in the early diagnoses of intracardiac thrombosis in LVAD patients. We attempt to provide a more dedicated method for the…
Primary Objectives: - To investigate whether disease progression in individual patients with CHF can be accurately assessed by serial measurements of disease-related (novel) biomarkers.- To investigate whether dynamic biomarker patterns as…
Primary Objective: -To test the feasibility of MRI and CT fusion with 3D rotational venogram / fluoroscopy for left ventricular lead positioning in CRT.Secondary Objectives: -Visualize the location and distance to LV lead position of MRI determined…
The primary objective of the present study is to demonstrate that NT-proBNP guidance during in-hospital treatment for acutely decompensated heart failure (to strive for >30% reduction) reduces readmissions and mortality and increases the…
Is to identify the incidence and prevalende of PH in premature born infants. In addition we will identify possible risk factors for the development of PH and we want to determine the prognosis and survival of these patients. PrimaryTo determine the…
Primary Objective: Evaluation of the benefit of IABP counterpulsation in patients with diuretic-resistant congestive heart failure. Secondary Objective(s): - To lower the burden of disease/improve symptoms, to shorten duration of stay in the…
Objective with respect to patient care: Obese patients have an increased risk of developing heart failure. By gaining insight on the role of obesity in cardiac dysfunction it will be possible to provide a better risk stratification for the onset of…
Hypothesis - Our hypothesis is that TNF blocking medication improves cardiac function in patients with active RA. Objectives - Primary objective: to investigate the effect of TNF blocking therapy on diastolic left ventricular (LV) function in RA…
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
To determine the tacrolimus bioavailability after tacrolimus administration via a rectiole.