412 results
1. To estimate the additional value of early MRI monitoring for the prediction of neurological outcome of comatose patients after cardiac arrest. 2. To gain insight in the pathophysiology of PAE by functional MRI measures and by associating MRI…
Research QuestionThis study is designed to describe PAH patients in terms of their clinical characteristics, therapies used, disease progression, and outcomes (eg, death, hospitalization, risk category for predicted mortality risk [Boucly 2017;…
2.1 Primary objectiveThe primary objective is to determine whether perirenal adipose tissue thickness is increased in patients with HFpEF compared with age, sex and BMI-matched healthy controls2.2 Secondary objectivesThe secondary objectives are to…
Primary Objective:- To investigate the association between temporal evolutions of blood biomarkers and clinical adverse events, in order to produce a dynamic, individual, and accurate prediction model for patients with HFpEFSecondary Objective(s):-…
Evaluate the performance and safety of HASS 200 (HARMONY AORTIC STIMULATION SYSTEM) in treatment of heart failure subjects.
Assessment of the Axone micro quadripolar electrode for enhanced cardiac resynchronization therapy.A clinical study designed to obain the CE-mark.This new, quadripolar micro electrode allows for easier placement of the left ventricular lead,…
To assess the risk profile associated with the combined endpoint of all-cause mortality and HF hospitalizations in HF patients with LVEF >0.40.
To assess the course of microcirculatory disturbances during ECMO. Furthermore, we will evaluate the effect of implementation of ROTEM in terms of thrombotic and hemorrhagic events and the use of blood products in patients on ECMO.
To quantify the effect of ID on skeletal oxidative metabolism in patients with chronic HF with either preserved (HFpEF) or reduced (HFrEF) left ventricular ejection fraction.
To assess the uniqueness of diabetic cardiomyopathy (DCM) relative to other forms of cardiomyopathy using unsupervised clustering approaches based on deep phenotyping (clinical, imaging and biological) information. With the results of this study we…
To compare the accuracy of the above-mentioned methods in patients admitted to the ward or intensive care unit in estimating CVP and to investigate the correlation between the different methods.
Proof of Principle: to assess feasibility to measure; (1) a reproducible 1st thermal IDC, (2) at least 1 recirculation IDC using the FBG photonic sensor both peripheral and nasal. - to compare the acquired Stroke Volume (SV) and Cardiac Output (CO)…
To determine the effect of tailored exergaming for inactive patients with HF to reduce their sedentary time, improve their daily physical activity, exercise capacity, decrease frailty and improve health-related quality of life.
Aim of the studyThis is a proof-of-concept study to investigate the effects of rTMS (iTBS protocol) on working memory of people with memory impairments after a cardiac arrest in the past. We propose a series of single case experimental design (SCED…
To investigate whether an integrated pathway using TM for patients with HF and COPD results in a delayed decline or improved quality of life. Secondary objectives are level of self-management, patient satisfaction, compliance to the program and cost…
The objective of this study is to assess the safety and effectiveness of the WISE System (providing LV pacing) when used in conjunction with a co-implanted system (ICD, pacemaker, CRT-P, or CRT-D) for bi-ventricular (BiV) pacing for CRT in heart…
We aim to investigate ECPR in a prospective manner since earlier retrospective studies have suggested that application of ECPR during refractory arrest increases the chance of survival and decreases neurological damage. In a randomized, multi-center…
The primary objective and hypothesis is to assess whether the SP-GRIPFLOW Catheter is safe and performs as intended. The primary hypothesis is that blood flow through the catheters and cerebral perfusion during open surgical repair of the distal…
The general objective is to study gender differences in the magnitude of CRT response in a HF population with an equal distribution of women and man in order to examine the interrelationship among CRT effect, gender and baseline clinical factors (e.…
Primary objective: Determine correlation between RFS parameters (5 independent signal characteristics) and non-invasive hemodynamic parameters (estimated left ventricular end diastolic pressure, left ventricular ejection fraction, left ventricular…