412 results
Primary objective:1. To identify new and/or additional markers for predicting absolute (and/or functional) ID in chronic HF and compare these serum markers to the gold standard of BM iron staining. Secondary objectives:2. To investigate the…
Determining the optimum moment of 123-Iodine meta-iodobenzylguanidine (MIBG) myocardial scintigraphy
The purpose of this study is to investigate whether H/M ratios from late scans, performed earlier than 4 hours post-injection of MIBG, are comparable with those determined at 4 hours
The aim of the current study is to determine whether long-term follow-up in primary care, under the condition of initial optimization of pharmacological and non-pharmacological treatment at the specialized HF clinic is equally effective as long term…
To examine the long-term effects of a CT- and/or RT-induced premature menopause on BMD, cardiovascular status, neurocognitive function and QoL in female HL survivors.
Determine whether and to what extent changes in microvascular perfused boundary region and syndecan-1 and heparan sulfate plasma levels, as measures for glycocalyx damage, occur in survivors and non-survivors of CA during the re-warming phase of…
Primary Objective: Validation of the Fresenius BCM in pediatric dialysis patients for the assessment of TBW and ECW using dilution techniques as the reference methods.Secondary Objective: Validation of saliva sampling for bromide concentration…
In the current study we will re-examine the participants of the CODAM study in a second follow-up evaluation (12 yrs after baseline) in order to obtain further longitudinal information on the natural development of type 2 diabetes and cardiovascular…
The purpose of this study is to evaluate the implant procedure and feasibility of the Model 20066 LV lead. The proposed Model 20066 study will provide data to assess the safety and feasibility of the Model 20066 fixation concept. It is also expected…
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Is it feasible to measure mean systemic filling pressure (Pmsf) and ΔetCO2 secondary to an incubator tilt maneuver in newborn infants?
The objective of the AUGMENT-HF study is to provide evidence for the safety profile associated with the Algisyl-LVR* device and initial evidence for the efficacy of the device.
* To establish the feasibility (i.e. % of measurements with sufficient quality for analysis) of exercise echocardiography in CHF patients, focusing on left ventricular function (LVEF), myocardial tissue motion (intra- and interventricular…
To determine the (added) value of molecular imaging parameters for selecting patients that will benefit from CRT, specifically:-Phase standarddeviation-Summed infarct score-Innervation Heart/Mediastinum ratio
AKINESIS is a multi-center prospective, uncontrolled clinical study to assess the utility of a plasma NGAL test (Triage® NGAL Test) and a urinary NGAL test (ARCHITECT® Urine NGAL) in predicting worsening renal function in patients presenting with…
The main objective of the study is to investigate the physiological effects of high intensity interval training (HIT) at the skeletal muscle level by assessing skeletal muscle re-oxygenation, skeletal muscle metabolic recovery and re-oxygenation…
The purpose of this clinical inestigation is to verify the efficacy and safety of the CVRx Neo baroreflex Activation Therapy System in subjects with heartfailure.
To investigate the relation of a set of (bio)markers and response to Cardiac Resynchronization Therapy (CRT); the interrelationship as well as the potential predictive power of these (bio)markers on improvement and/or deterioration of cardiac…
This study will address the mechanisms of DHF by identifying the role of biomarkers in the process of neurohormonal activation, cytokine activation and oxidative stress, the role of biomarkers at myocardial level in the process of cardiomyocyte cell…
Objective: To establish LV and RV geometry and function, and tissue characterization in age-and gender-matched healthy controls (serving as reference group for the CFS patients) by using own CE-CMR imaging.
Primary objective • To explore changes in left ventricular ejection fraction (LVEF) values before, during and after trastuzumab treatment Secondary objectives• To explore the reversibility of congestive heart failure associated with trastuzumab…