386 results
1) To identify clinical and imaging predictors of recurrent stroke; 2) To improve early detection of small volume stroke with admission computed tomography perfusion (CTP) in patients with suspected acute ischemic stroke with small volume stroke or…
Primary Objective: The aim of this study is to compare efficacy of antiarrhythmic drugs (sotalol or combination of flecainide and verapamil) and catheter ablation in reducing VPB/VT burden in patients with symptomatic idiopathic VPB/VTs.
The primary objective of the study is to explore the possibilities measurement of STV-ARI on human intracardiac signals, to compare this with the STV-QT on the surface ECG during sinus rhythm and while pacing the heart with different frequencies.
To determine the lowest energy which successfully converts induced ventricular arrhythmias in S-ICD patients who underwent elective generator replacement and compare these data to average DFT results in de novo S-ICD patients from previous studies.
To assess the safety, feasibility, and tolerability of the Vine* Embolic Protection System and implantation procedure in atrial fibrillation (AF) patients at high stroke risk who are unsuitable for oral anti-coagulants (OAC).
Primary Objective: to obtain reliable estimates of the rates of vascular death and non-fatal stroke in patients with atrial fibrillation and a recent anticoagulation-associated ICH who are treated with apixaban versus those who are treated with APDs…
The aim of this pilotstudy is to obtain data regarding feasibility, safety and costs of home-based electrical cardioversion
2.2 Primary ObjectiveTo study clinical factors, (blood) biomarkers and genetic markers related to AF progression in patients diagnosed with recent onset self-terminating AF with special reference to hypercoagulability.2.3 Secondary Objectives1. To…
To demonstrate superiority of left ventricular septal pacing over right ventricular pacing and to investigate the additional effect of capturing the left bundle branch in left ventricular septal pacing (LVsP). This will be done by studying…
The primary objective of the TactiFlex PAF IDE clinical trial is to demonstrate that ablation with the TactiFlex* Ablation Catheter, Sensor-Enabled* (TactiFlex SE), in conjunction with a compatible RF generator and three-dimensional mapping system,…
Objective of the study is to measure dabigatran trough levels, percentage of dabigatran glucuronidation, and diluted thrombin time, to test whether these levels are different in elderly patients.
Primary Objective: To prospectively identify parameters correlated with Cerebral Performance Category (CPC)* * 2 at hospital discharge. Secondary Objective(s): - Parameters correlated with a CPC*1 * 2, 6 months after arrest- Parameters correlated…
The objectives of this study are: 1) to assess the feasibility, accuracy and efficacy of simultaneous, conventional and micro-electrode mapping using the QDOT catheter to delineate and ablate the functional substrate of post-MI VT compared to…
The objective of this study is to determine the performance, as defined by sensitivity and specificity, of the commercially available Apple Watch-based electrocardiographic registration to identify AF during tachycardia, validated against the gold…
Primary ObjectiveThe goal of the study is to evaluate hemostasis (i.e. coagulation activation, platelet reactivity, overall thrombus formation and fibrinolysis) following LAAO in a longitudinal design for hypothesis-generating purposes. Several…
To determine the ratio of parent drug to metabolites in the circulation.Profiling of [14C]-etripamil metabolites in blood, urine and feces.To determine the mass balance of drug-related materials following intranasal administration.To determine the…
Primary:1. The primary objective is to evaluate the safety of self-administered etripamil nasal spray (NS) outside of the clinical settingSecondary Objectives:1. To evaluate the efficacy of self-administered etripamil NS outside of the clinical…
Primary Objective: The primary objective of the pilot study is to evaluate the feasibility and acute efficacy of irreversible electroporation for pulmonary vein antrum isolation in patients with atrial fibrillation:- Acute pulmonary vein isolation…
Primary objective of this study is to investigate the possible correlation between non-invasive strain(rate) measurements with speckle tracking in the left atrium and invasive voltage measurements in the left atrium. Secondary abjectives are to…
Safety and feasibility of IRE for PVI