386 results
The aim of this study is to investigate the acute and long-term efficacy of the second generation CB after with a follow up range of 1-5 years follow up. In a cohort of patients with drug resistance persistent atrium fibrillation.
First-In-Human Clinical Investigation to evaluate the safety and performance of the Adagio Medical PFA and PFCA Systems in the ablation treatment of symptomatic Persistent Atrial Fibrillation (PsAF).
The current trial aims to assess and validate atrial fibrillation detection and monitoring by the Corsano CardioWatch 287-2 in a remote setting across multiple international centres. By: a) To compare episodes of atrial fibrillation across 30-second…
The primary objective of this explorative study is to investigate the effect of 3-month preparation period of regular walking exercise prior to the Nijmegen 4-Day marches on objectively measured AF burden (primary parameter), self-reported AF burden…
Irregular heart rate can be detected with a camera-based monitoring technology.
Renal artery denervation (RDN) on top of pulmonary vein isolation (PVI) will improve the success of ablative therapy for patients who have paroxysmal and/or persistent atrial fibrillation, with out of range hypertension (systolic >140 mmHg or…
We aim to observe in whole blood at patients core temperature and normotemperature how mild therapeutic hypothermia affects coagulation and in particular fibrinogen, in post cardiac arrest patients.
The objective of this study is to investigate cardiac sympathetic ativity in subjects with 22q11DS and the effect of catecholamine depletion.
Evaluation of the long term results of surgical carotid denervation in patients suffering from CSS.Primary question:Is surgical denervation an effective treatment option for symptoms caused by CSS, eg dizziness and syncope, on the long term.…
Primary objective: to identify intra-individual changes of clinical and biochemical markers of AT characteristics before, and one year after bariatric surgery by:* Determining circulating AT derived biomarkers * Determining local AT biomarkers in…
The major objective of this clinical investigation is to demonstrate safety and effectiveness of the ablation system (OMNYPULSE* Bi-Directional Catheter and TRUPULSE* Generator) when used for isolation of the atrial PVs in treatment of subjects with…
To assess the prevalence of subclinical AF in obesity patients by using different contemporary AF-detection applications (primary objective). To investigate the potential role of GLS as a parameter to predict presence of AF in obesity patients (…
The objective of the study is to confirm the long-term safety of the Tendril STS and Isoflex leads, implanted with the Assurity MRI* or Endurity MRI* pacemakers, in patients undergoing clinically indicated 3T MRI scans.
The primary objective of this study is to determine if left atrial appendage closure with the WATCHMAN FLX device is a reasonablealternative to non-vitamin K oral anticoagulants (NOACs) in patients with non-valvular atrial fibrillation.
The primary objective involves comparison of the sensing performance of surface and subcutaneous ECGs at rest, and comparison of sensing performance of surface and subcutaneous ECGs during exercise.
This study will investigate the effects of renal nerve stimulation before and after percutaneous transluminal renal denervation on cardiac excitable properties including induction of ventricular tachy-arrhythmias before and after renal denervation…
The objective of this validation study is to determine whether the wearable sensors: HealthPatch, SensiumVitals and the bed-based contact-less EarlySense system are able to detect heart rate and respiratory rate in a clinical setting, with…
Objective of the INFINITE 2 MRI Study is to collect data on the ImageReady* MR Conditional Pacing System in subjects already implanted with the system according to standard medical guidelines for PM implantation and meets the labeled MRI Conditions…
To compare the effectiveness of PVI and VATS-PVI. Secondary objectives are to compare the duration of hospitalisation, quality of Life, cost and to compare the satisfaction of the patients.
Objective of the INFINITE MRI Study is to collect data on the ImageReady* MR Conditional Pacing System in subjects already implanted with the system according to standard medical guidelines for PM implantation and meets the labeled MRI Conditions of…