386 results
This study is intended to assess the safety and performance of the ACT Catheter for ablation of right atrial isthmus dependent flutter, also known as typical atrial flutter.
Objectives: 1/. To study the proarrhythmic effects of intracellular Ca2+ signaling alterations in AF.2/. To study the nuclear Ca2+ signaling in AF.3/. To study the Ca2+-dependent pathways activated in AF and the consequences of the inactivation of…
The present study is designed to test the hypothesis that new imaging modalities like PET with the use of HED and contrast enhanced CMR to quantify fibrosis size and heterogeneity of scar tissue can give a further risk stratification for ventricular…
Primary Objective: The main objective of this study is to demonstrate that PVC suppression therapy on top of conventional heart failure treatment improves cardiac systolic function as assessed by quantitative echocardiography in patients with…
This amendment (extension to CRT-D subjects) aims to assess the economic effects of HM technology vs. classical follow-up of CRT-D patients from two perspectives: 1) the cost-effectiveness for the payer of health care, and 2) the economic impact on…
The general objective of the intervention trial will be to evaluate the effect of this web-based behavioral intervention on psychological outcomes (i.e., anxiety and quality of life), physiological parameters (i.e., ventricular arrhythmias and…
This study has three objectives:1. To describe flow patterns in the left atrium in patient with sinus rhythm and atrial fibrillation. 2. To prospectively verify the data in patients with atrial fibrillation3. Correlation of abnormal flow patterns to…
The objective of this study is to determine the effectiveness of the CHA2DS2-VASc prediction model as directive for the preventive management of AF patients in the first line.
Objective: The aim of this study is to investigate the in-vivo variability of hemostasis between patients when treated with a direct thrombin inhibitor (Dabigatran) or a direct Factor Xa (FXa) inhibitor (Rivaroxaban) by measuring thrombin generation…
The objective of this study is to assess the risk profile which represents the degree of changes in the atrial tissue andwhich can help predict in which patients rhythm control will be successful. This risk profile will consist of a combination…
The objective of this study is to determine the frequency of previously undiagnosed SCN5A mutations leading to sudden death in temporal association with vaccination in The Netherlands.
To identify patients who are not suitable for S-ICD implantation based on QRS/T-morphology analysis during exercise, although they passed the QRS/T-morphology screening in rest.
Non-invasive localization of the site of origin of idiopathic ventricular arrhythmias
Objective of the INFINITE MRI Study is to collect data on the ImageReady* MR Conditional Pacing System in subjects already implanted with the system according to standard medical guidelines for PM implantation and meets the labeled MRI Conditions of…
See protocol page 23This study is designed to assess the usability and functionality of the Reveal LINQ system. Data from the first 30 patients, with 30 days of follow-up, will be used to assess sensing performance and wireless capabilities of the…
See protocol page 12The purpose of this clinical study is to evaluate the safety and efficacy of the Micra Transcatheter Pacing system and to assess long-term device performance.
This study is a prospective, non-randomized, single-center study evaluating the correlation between the respiratory rate derived from the Reveal Insertable Cardiac Monitor (ICM) electrocardiogram (ECG) with the respiratory rate obtained from an…
The purpose of this clinical study is to confirm safety and effectiveness of the Medtronic 5076 lead when used with Medtronic*s AdvisaDR MRI pacemker in the clinical MRI environment.
The objective of the study is to demonstrate that the creation of cardiac lesions with epicardially applied RF ablation through a minimally invasive surgical (MIS) approach plus EP ablation performed when needed at least 3 months later enhances the…
See protocol page 9This study designed to determine, via continuous monitoring with the Reveal XT implantable cardiac monitor (ICM) or newer approved version, the incidence of atrial fibrillation (AF) in patients suspected to be at high risk for…