33 results
The aim of this study is to determine if adding ablation restricted to specific areas of the left atrium to PVAI is superior to the standard care PVAI alone.
To compare the EEG pattern after administration of cyclopentolate with the EEG pattern after placebo eye-drops.Primary outcomeEEG pattern changes after administration of two drops of cyclopentolate1% compared with placebo.Secondary outcomes- Pattern…
To demonstrate that ventricular tachycardia (VT) ablation using the Niobe* ES system results in superior outcomes compared to a manual approach in subjects with ischemic scar VT in a low ejection fraction population.
This study will provide data on fluoroscopy exposure, use of contrast agents and effectiveness of the combined use of cryoballoon ablation and 3D CT overlay
Verification of number of mode switches, Verification of undersensing of AFor other ATAs. Incidence of mode switches due to FFRW oversensing using Accent pacemaker in the most sensitive sensing setting(s)using the Optisense vrs Tendril lead
Effectiveness: To provide valid scientific evidence that use of the TactiCath® Set is an effective treatment for symptomatic paroxysmal atrial fibrillation (PAF).Safety: To provide valid scientific evidence that use of the TactiCath® Set is safe as…
To perform a pre-study to assess the feasibility of DE-MRI to assess lesion size, transmurality and completeness of pulmonary vein isolation. The study will be performed to determine if and how DE-MRI can be used in a larger subsequent multicentre…
This study aims at investigating the role of autonomic modulation of AF. Therefore, totally thoracoscopic PV isolation with additional ablation of ganglionated plexi (GP) will be studied against PV isolation alone. Two groups of patients (paroxysmal…
1. To determine the level of cognitive, emotional and cardiorespiratory impairment, daily functioning, participation in society, quality of life and partner strain up to one year after the survival of a cardiac arrest.2. To determine prognostic…
To demonstrate the arrhythmogenic action of MSG in a single blinded placebo controlled test on these patients with reported MSG induced AF and to investigate the possibility of MSG as a potential trigger for AF.
The trial will test the hypothesis that ICD implantation without defibrillation testing (DT) is non-inferior to implantation with testing against the composite endpoint of ineffective first appropriate clinical shock or arrhythmic death.
NOACs have no need for regular monitoring, this could have an effect on adherence. It is our objective to study adherence and patient satisfaction in WIPPS guided and non-WIPPS guided patients using Rivaroxaban
The intent of this study is to evaluate the safety and efficacy of the implanted Accent MRI system, which includes the investigational St. Jude Medical Tendril MRI* lead and Accent MRI* pacemaker, in the MRI environment. An MRI Activator* will be…
Concomitant AF ablation with HIFU in patients with persistent or long standing persistent AF undergoing CABG will be superior in restoring SR, compared with patients with persistent or long standing persistent AF undergoing CABG treated with best…
Primary study objective:The primary objective of this study is to evaluate the clinical outcome of dual-chamber ICD therapy with minimized ventricular pacing compared with single-chamber device therapy with settings which are common in clinical…
To determine whether a dosing algorithm containing genetic information increases the time within therapeutic INR range during anticoagulation therapy with phenprocoumon compared to a dosing regimen that does not contain this genetic information.…
The main objective of this study is to compare the occurrence of next ICD shock therapy for VT or VF in patients with hospital presentation for an ICD shock therapy for VT or VF, with a history of a myocardial infarction, between patients randomized…
To determine whether a dosing algorithm containing genetic information increases the time within therapeutic INR range during anticoagulation therapy with acenocoumarol compared to a dosing regimen that does not contain this genetic information.…
The purpose of this study is to evaluate and document that the clinical performance of the TELIGEN 100 HE and COGNIS 100 HE systems and associated application software is within design specifications. It will also document the appropriate clinical…
The primary study objective is to compare the rate of major CIED infections through 12-months post-implant between the TYRX envelope group and the control group.