131 results
Primary objectivesTo show that a model incorporating the novel predictors BSPM, TE-ECG and SNPs is superior to existing models in predicting maintenance of sinus rhythm after successful DCC in patients with persistent AF.Secondary objectivesTo…
Primary Objective:To demonstrate that the AlCath Flux eXtra Gold ablation catheter is non-inferior compared to historical datafrom the literature regarding the prevention of new subclinical cerebral thromboembolic lesions after PVI.Secondary…
In this study, the main clinical hypothesis is that the TIMI clinically significant bleeding rates will not be different between the rivaroxaban and VKA treatment strategy groups at Month 12.
Primary Objective: to determine the prevalence of MTWA in adults with congenital heart disease who are deemed to be at high risk for ventricular arrhythmias and sudden cardiac death.Secondary Objective(s): • to describe the clinical usefulness and…
We hypothesize that verapamil reduces progression from paroxysmal to persistent AF, improves rate control, exercise tolerance and quality of life and reduces costs compared to metoprolol.
Primary objective: To compare at baseline the exact phenotypes of patients with young AF with versus without familial AF. Assessment of the phenotype includes clinical characteristics, presence of validated AF risk factors, (electro-)…
Primary Objective: to compare the atrial contractility by means of echocardiography between patients receiving flecainide and vernakalant i.v. after conversion to sinus rhythmSecondary Objective(s): 2a. To compare the conversion rate of AF between…
The primary objective of this study is to validate that the reduced system dose setting with Xres4 translate into an overall procedure dose reduction. Procedure dose will be determined by the cumulative dose area product (DAP) value and the…
To investigate whether high resolution multi-site epicardial mapping of the atria in patients with structural heart disease undergoing cardiac surgery can identify patients at risk for developing early post-operative atrial fibrillation. The…
Choosing the most suitable laboratory test and setting up a gold standard test to measure dabigatran. Additionally, determining maximal and minimal concentrations of the drug.
1. Primary objectiveThe identification and discrimination of AF burden and the patient burden of the nECG system in patients with paroxysmal AF undergoing catheter ablation for AF.2. Secondary objectiveAssess the relation between the changes in…
The purpose of this investigation is to determine the prevalence of device-recorded ST segment changes occurring before appropriate ICD therapies (ATP or Shock) and to define their temporal relationship to ventricular arrhythmias.
St. Jude Medical developed the Merlin.net* Patient Care Network (Merlin.net* PCN) to augment or replace routine scheduled in-clinic visits. This investigation is designed with the hypothesis that detection of events (system integrity and diagnostic…
We aim to observe in whole blood at patients core temperature and normotemperature how mild therapeutic hypothermia affects coagulation and in particular fibrinogen, in post cardiac arrest patients.
Primary Objective: to show that TVI of the atrial wall during ongoing AF may be used to predict long-term progression to (or recurrence of) persistent AF in patients with paroxysmal and persistent AF undergoing rhythm control.Secondary Objective(s…
Demonstrate that the remote management system (Carelink, study group) reduces the time from device detected event onset to clinicaldecision for arrhythmias, cardiovascular disease progression,and system issues compared to patients receiving only in-…
Time to recurrence of sustained VT and/or appropriate ICD therapy; ATP or shock
The primary objective of this study is to demonstrate that the efficacy of rivaroxaban, a direct FXa inhibitor, is non-inferior to that of dose-adjusted warfarin for the prevention of thromboembolic events in subjects with non-valvular atrial…
To demonstrate the arrhythmogenic action of MSG in a single blinded placebo controlled test on these patients with reported MSG induced AF and to investigate the possibility of MSG as a potential trigger for AF.
The objective of this study is to assess the risk profile which represents the degree of changes in the atrial tissue andwhich can help predict in which patients rhythm control will be successful. This risk profile will consist of a combination…