261 results
To investigate the association between shear stress and plaque growth and plaque composition changes over time. Furthermore, it will be investigated how these plaque changes influence the local wall stress.
This study aims at establishing the influence of sampling site on the variability of ACT measurement at the end of coronary angiography or PCI.
In the present study we aim to determine the value of microvascular resistance measurements in the acute setting to predict the occurrence of MVO in the following days, using the combined pressure-flow wire. Therefore patients with an acute MI will…
The primary objective of this study is to assess whether a liberal (6.5 mmol/l) transfusion strategy compared to a restrictive (6.0 mmol/l) transfusion strategy lowers the incidence of major adverse cardiac events (MACE). MACE is defined as a…
To determine whether CCTA can provide a more efficient diagnostic work-up in suspected NSTE-ACS patients with an initial inconclusive work-up by identifying patients that do not have significant coronary artery disease.
The objective is to study the feasibility of different PET tracers to detect vulnerable plaques in patients with a recent acute coronary syndrome and co-localize these inflammatory lesions with anatomical plaque features obtained with CT based…
Primary Objective:- To assess lipid levels of STEMI patients over a long course. Secondary Objectives:- To assess the association between poorly controlled cholesterol and (apo) lipoprotein levels for the long term outcome in STEMI patients.- To…
To determine the added value of signs, symptoms and H-FABP measurement in in- or excluding acute coronary syndrome in patients with thoracic complaints in general practice
Primary Objective: • To study the accuracy of a combined CT angiography and DECT for complete imaging of CAD compared to the reference standard, ICA and SPECT MPI. Secondary Objective(s): • To compare DECT analysis in the detection of perfusion…
The aim of this study is to investigate whether iFR-measurement of non-infarct related arteries during the acute phase of STEMI is in agreement with iFR and FFR measurement at the staged procedure.
The Lipid-rich Plaque Study will be performed in patients undergoing IVUS-NIRS imaging (the index procedure) in whom a TVC catheter will be purchased and used for routine clinical indications. The study will test the ability of multi-vessel NIRS…
1. The primary objective is to assess the effects of four 250 mg PC-mAB (also referred to as "3G10") once monthly intravenous injections on monocyte function ex vivo. The secondary objectives are to:1. assess the functional effects of 3G10…
1) To evaluate changes in microvascular resistance of the infarcted area in the first hours after ST-elevation myocardial infarction and during the recovery period (<5 days)2) To classify patients according to recovery of microvascular…
To compare the image quality, visibility of perfusion deficits and myocardial blood flow of a conventional analog PET system with a digital PET system in 30 patient referred for PET myocardial perfusion imaging (MPI).
- To compare relative myocardial mass distribution (i.e. mass of the respective territories of LAD, LCX and RCA) by CT scanning to normalized hyperemic blood flow in the three major myocardial territories as assessed by absolute flow measurements…
This study aims at establishing the influence of sampling site on the variability of ACT measurement at the end ofcoronary angiography or PCI.
To assess whether the iFR is non-inferior to FFR when used to guide treamtent of coronary stenoses with PCI
To investigate whether children with a history of Kawasaki disease have an increased IMT and arterial stifness compared to their healthy siblings.
To determine whether platelet reactivity unit (PRU) values as assessed with the VerifyNow P2Y12 assay are influenced by the performance of a PCI procedure
To compare the diagnostic value of CTA versus the standard work-up in terms of identifying patients with severe coronary artery disease (requiring revascularization), as well as the ability to safely discharge patients without coronary artery…