277 results
In patients with NSTEMI we aim to: 1) compare coronary vulnerable plaque detection between 18F-NaF-PET-CMR and invasive coronary angiography, 2) investigate the relation of coronary vulnerable plaques using 18F-NaF-PET with myocardial infarction…
To investigate the association between shear stress and plaque growth and plaque composition changes over time. Furthermore, it will be investigated how these plaque changes influence the local wall stress.
This study aims at establishing the influence of sampling site on the variability of ACT measurement at the end of coronary angiography or PCI.
Describe the relation between patterns in biomarkers of vascular inflammation, plaque instability and hypercoagulability and the incidence of recurrent ACS
In the present study we aim to determine the value of microvascular resistance measurements in the acute setting to predict the occurrence of MVO in the following days, using the combined pressure-flow wire. Therefore patients with an acute MI will…
The main objective of this study is to assess the effect of an acute cardiovascular event on the local and the systemic inflammatory state in humans with AMI as well as the reversibility of these effects after 3 months.
To answer the following research questions: 1. Do intimal arterial calcification and medial arterial calcification in the lower extremity arteries increase the occurrence of cardiovascular disease in people with a high risk of cardiovascular disease…
Determining the role and influence of genetics, their polymorphisms and immunologic phenotype in arteriogenesis in patients with obstructive coronary artery disease (CAD).
To determine whether CCTA can provide a more efficient diagnostic work-up in suspected NSTE-ACS patients with an initial inconclusive work-up by identifying patients that do not have significant coronary artery disease.
The objective is to study the feasibility of different PET tracers to detect vulnerable plaques in patients with a recent acute coronary syndrome and co-localize these inflammatory lesions with anatomical plaque features obtained with CT based…
To determine the added value of signs, symptoms and H-FABP measurement in in- or excluding acute coronary syndrome in patients with thoracic complaints in general practice
Primary Objective: • To study the accuracy of a combined CT angiography and DECT for complete imaging of CAD compared to the reference standard, ICA and SPECT MPI. Secondary Objective(s): • To compare DECT analysis in the detection of perfusion…
To prevent vessel damage of the radial artery by using the Cordis Railway sheathless guiding catheter system.
The goal of this pilot study is to investigate whether circulating monocytes of patients with MCD are characterized by a trained phenotype, so we can ascertain whether trained innate immunity may contribute to microvascular wall inflammation in…
The aim of this study is to investigate whether iFR-measurement of non-infarct related arteries during the acute phase of STEMI is in agreement with iFR and FFR measurement at the staged procedure.
1) To evaluate changes in microvascular resistance of the infarcted area in the first hours after ST-elevation myocardial infarction and during the recovery period (<5 days)2) To classify patients according to recovery of microvascular…
To compare the image quality, visibility of perfusion deficits and myocardial blood flow of a conventional analog PET system with a digital PET system in 30 patient referred for PET myocardial perfusion imaging (MPI).
to identify novel molecular pathways resulting in premature atherosclerosis (PAS) in families where the traditional risk factors are not present / near absent.
- To compare relative myocardial mass distribution (i.e. mass of the respective territories of LAD, LCX and RCA) by CT scanning to normalized hyperemic blood flow in the three major myocardial territories as assessed by absolute flow measurements…
This study aims at establishing the influence of sampling site on the variability of ACT measurement at the end ofcoronary angiography or PCI.