23 results
Primary objective: To investigate left ventricular diastolic function in AS-patients compared with osteoarthritis patients. Secondary objectives: To assess the prevalence of valvular heart diseases and conduction disturbances. To assess left…
Within this project we aim to determine the energetic conditions that underlie the transition to hypertrophy of the HOCM heart. A prospective comparison will be made between results of PET, MRI and function of cardiac myofilaments (in vitro). Also,…
We hypothesize that the amount of physical activity correlates with insulin-induced microvascular recruitment during free-fatty acid infusion in skeletal muscle as well as in the heart. In this study we aim to test this hypothesis.
To assess the effects of marathon running on changes in cardiac and skeletal muscle structure and function using state of the art MRI techniques, ultra-sensitive biomarker assays and a high resolution 64-lead electrocardiogram.
The purpose of the sub-study is to do research into markers which will hopefully assist to diagnose the condition Peripartum Cardiomyopathy as early as possible. The blood donated for research will also assist in the assessment of women having a…
The main objective of this study is to evaluate whether myocardial ischemia in the absence of obstructive CAD in athletes is associated with a reduced myocardial perfusion when compared to control subject with a low a priori risk of CAD and without…
The aim of this study is to investigate the temporal dynamics between depressive symptoms and physical activity in post-MI patients, in order to prevent the deleterious effects of depression on heart disease prognosis and improve patient counselling…
The aim of this study is to identify risk factors for various CVDs, i.e. to quantify separate and joint effects of radiation dose to the heart, anthracycline dose, other CT, life style factors, established CVD risk factors and genetic susceptibility…
a) to study if biochemical evidence of myocardial injury is associated with impaired myocardial function and to study potential determinants, and b) to study if impaired myocardial function is associated with the need for vaso-active support
To assess cardiovascular structure and function, physical capacity and traditional CVD risk factors in i) physical active subject with MI and ii) physical active subjects without MI.
The primary objective of this study is to determine whether glucagon-mediated activation of the calcineurin-pathway is associated with LVH in severely insulin-resistant diabetic subjects.
- To identify the causes of inflammation of adipose tissue, liver and blood leukocytes by focusing on the contribution of the gut microbiota taking into account dietary habits and genetic background.- To assess the influence of inflammation of…
The aim of the research is to enroll 100 consecutive untreated periodontitis patients for the normal standard treatment. We will investigate by means of venous blood analyses before treatment and 3, 6, and 12 months after treatement whether plasma…
Our first objective is obtaining hypertrophic myocardial tissue for identifying novel biomarker, indicative and predictive for the severity of cardiac hypertrophy. Our second objective is validation of biomarkers detected in previous studies.
To determine the effect of RIPC on MINS in patients after pancreatic sugery.
The primary objective is to study the association between baseline (including genetic), and repeatedly measured blood biomarkers (including metabolomics and proteomics), and the incidence of cardiovascular disease. Secondary objectives are related…
The main objective is to pinpoint the biological pathways that set long-term risk of CVD and NDI when epigenetically disturbed during fetal development by (1) establishing a longitudinal cohort of MC twins, (2) defining epigenetic alterations…
Primary objective To investigate and compare the independent prognostic effects of the different PMI phenotypes (myocardial infarction and noninfarct troponin elevation) and noncardiac MAPE on disability in patients undergoing elective noncardiac…
To determine whether a standardized exercise workload elicits a different response on 1) metabolites/cardiac biomarkers in the general circulation (measured by blood values), and 2) contraction patterns in local myocardium (measured by…
The main objective is to assess long-term neurodevelopmental, cardiovascular, pulmonary, and growth outcomes in a cohort of MC twins with sFGR and to compare outcomes within sFGR twin pairs.