146 results
To examine the effect of remote ischemic preconditioning on exercise-induced cTn elevations and indices of cardiac function.
The feasibility of direct-detection of fibrotic tissue will be assessed in patients with a healed myocardial infarction and in patients with cardiomyopathy using LGE as reference standard.
To assess whether an extension of the cardiac rehabilitation program with telemonitoring guidance results in better long term effects on physical and mental outcomes than a regular follow-up period after traditional cardiac rehabilitation.
The project determines the value of a novel method of measuring cardiac cTnI at the patient*s bedside (point of care testing). The study aims to assess the analytical and clinical performance of a point of care troponin I test using an novel…
To determine whether aleglitazar reduces cardiovasculair mortality and morbidity (defined as non-fatal myocardial infarction (MI) and non-fatal stroke) in patients with a recent ACS event and type 2 diabetes.
To assess the impact of eplerenone on cardiovascularmortality and morbidity in patients with acutemyocardial infarction (STEMI) when initiated withinthe first 24 hours of onset of symptoms (preferablyduring the first 12 hours)To investigate the…
The objective of this study is to determine the Safety and Efficacy of ADRCs delivered via the intracoronary route in the treatment of patients with ST-elevation acute myocardial infarction (STEMI).Investigation of stem and regenerative cell therapy…
To compare cerebral activity patterns during emotional and cognitive processing among patients with post-MI depression and patients with regular depression.
The aim of this study is to investigate the temporal dynamics between depressive symptoms and physical activity in post-MI patients, in order to prevent the deleterious effects of depression on heart disease prognosis and improve patient counselling…
The aim of this study is to identify risk factors for various CVDs, i.e. to quantify separate and joint effects of radiation dose to the heart, anthracycline dose, other CT, life style factors, established CVD risk factors and genetic susceptibility…
Procedural success, comprising insertion of the Stentys SDS, deployment of the Stentys Sent in the main branch, withdrawal of the Stentys SDS and creation of the Stentys Sent opening for the sidebranch, without major adverse cardiac events during…
The primary efficacy objective of this study is:• To evaluate the efficacy of RO4905417 in reducing the procedural damage during PCIThe secondary efficacy and safety objectives of this study are: • To evaluate the changes in other cardiac and renal…
1) To demonstrate an elevated troponin concentration before exercise and a rise of troponin after exercise in both pre-clinical HCM mutation carriers and HCM patients with the hypertrophic phenotype, 2) To evaluate the troponin rise in relation to…
The primary objectives of the study is to test the hypothesis that in healthy volunteers RIPC (bilateral forearm ischemia and reperfusion) reduces troponin I appearance in plasma in response to a high intensive bicycle exercise test.
1. Creating a reproducible and valid method for adenosine measurement2. Studying the effect of dipyridamole on the endogenous adenosine concentration before and after CPT.
a) to study if biochemical evidence of myocardial injury is associated with impaired myocardial function and to study potential determinants, and b) to study if impaired myocardial function is associated with the need for vaso-active support
To determine whether perioperative myocardial ischemia is associated with adverse outcome in patients scheduled for major abdominal surgery.
We hypothesised that cardiovascular changes already exist in children with cystic fibrosis compared with healthy control children. Therefore, we will evaluate the cardiovascular system in a group of children with cystic fibrosis compared with…
Objective of this study is to determine (1) whether mindfulness training has an additional clinical and psychological effect to standard care, and (2) whether offering mindfulness training is a cost-effective intervention, in adult patients with…
To assess cardiovascular structure and function, physical capacity and traditional CVD risk factors in i) physical active subject with MI and ii) physical active subjects without MI.