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How effective is local treatment of Molluscum Contagiosum compared to whatchful waiting?

The aim of this study is to compare the effect of early treatment on healing and quality of life with the usual expectant policy in children with mollusca contagiosa.

Autologous cell suspension grafting using ReNovaCell in non-segmental vitiligo patients: a randomized controlled study

Primary: to assess the efficacy and safety of RenovaCell grafting combined with 311 nm UVB therapy and topical anti-inflammatory therapy for the treatment of stable non-segmental vitiligo. Secondary: to assess, satisfaction, cosmetic acceptability,…

Is Medical Moisture Retention Creme more effective than cetomacrogol creme FNA for treatment of veneus eczema? A single blinded, randomised controled study in the wound treatment centers in the Netherlands

Studying whether the effectiveness of Medical Moisture Retention Cream (Alhydran®) is greater than that of Cetomacrogolcrème FNA on duration healing of matig ernstig venous eczema, as well as reduction of the complaints associated with venous eczema

A single (assessor) blinded, randomized, parallel-group, monotherapy trial to evaluate the pharmacokinetics and safety of tralokinumab in children (age 6 to <12 years) with moderate to-severe atopic dermatitis.

Primary objective: To establish the PK profile after multiple SC administrations of tralokinumab in children with moderate-to-severe AD.Secondairy objectives: - To assess the safety and tolerability of multiple SC administrations of tralokinumab in…

A Prospective Randomized Multicenter Single Blinded Study to Assess the Safety and Effectiveness of the SELUTION SLR* 014 Drug Eluting Balloon in the Treatment of Below-the-Knee (BTK) Atherosclerotic Disease in Patients with Chronic Limb Threatening Ischemia (CLTI)

To demonstrate superior efficacy and non-inferior safety of the SELUTION SLR 014 DEB compared to PTA (uncoated balloon) in the treatment of peripheral arterial disease (PAD) in the BTK arteries in CLTI patients.

A preliminary study on the effect of photothermal laser therapy on the vascularization and innervation of psoriatic lesions*

This project aims to assess the effect of laser therapy on the blood vessels and (peripheral) innervation of psoriasis plaques. The primary objective is to quantify the regression and recovery of nerves compared to blood vessels. We hypothesize that…

The effect of Hypbaric oxygen therapy in the treatment of hidradenitis suppurativa: a randomised controlled trial

To find a suitable treatment option for the 25% of HS patients who are therapy-resistant. Additionally, we expect a faster healing time of the wounds, meaning that even if patients respond to current treatment, HBOT may improve their quality of life…

A randomized, single-blind, saline-controlled, dose-finding, study to characterize the pruritus and inflammatory response to intradermal histamine in healthy volunteers and patients with atopic dermatitis

Primary objectives • To characterize the histamine dose response on pruritus• To profile the response to intradermal histamine by:o Clinical measureso Biophysical measureso Imagingo Molecular and cellular responsesSecondary objective • Comparison to…

The UPDATE trial (Uvb Phototherapy in Dermatology for ATopic Eczema): A multicenter randomized controlled trial of narrowband UVB versus optimized topical therapy in patients with atopic eczema.

Comparing the effectiveness and cost-effectiveness of narrowband ultraviolet B with optimal topical therapy (NB-UVB+OTT) versus OTT at 3 months in adult patients with atopic eczema (AE).