59 results
Analyses should indicate whether, in line with our hypotheses, CIM and CPM are improved after effective treatment in patients with chronic itch. When the hypotheses are supported, the study provides preliminary evidence for possible treatment…
To gain insight in the effects and cost-effectiveness of the introduction of laser Doppler imaging in burn care.
The objective of this study is to find out the relevance of adding isobornyl acrylate to the (meth) acrylate. Sub question: What is the relevant test concentration of isobornyl acrylate?
A pilot-study to the feasibility of a simple self-patchtest with a PPD containing hair-dye solution. The aim is to investigate whether a 30-minutes application of a patch-test gives a positive reaction in individuals who have a proven contact…
What is the proportion of STI outpatient clinic visitors with a persistent colonisation of chlamydia in the pharynx up until 3 weeks after the first diagnosis based on a NAAT positive chlamydia pharyngeal swab.
The purpose of this study is to determine whether psoriatic arthritis (PsA) can be detected in an early stage by the dermatologist, with the diagnosis of the rheumatologist as a "gold standard" for presence of this disorder. Futhermore it…
With this study we want to validate the negative pressure instrument which can make suction blisters, so in the future it can be used for other purposes. It can be helpfull to study the effects of medication or other treatments on blister formation…
The aim of this study is to develop and validate the basophil activation test by flow cytometry in our hospital as an extra diagnostic procedure for patients, who can not be diagnosed with existing tests or who have the risk of developing…
The objective is to assess the effect of adalimumab on selfconfidence and sexuality of patients with anogenital psoriasis.
To investigate whether the T cell profile of T cells in inflamed skin of psoriasis patients is identical or not to inflamedskin/synovium in psoriatic arthritis patients . All this in comparison to healthy controls. By determining the clonality and…
To determine whether we should add ascaridole to the patch test and to differentiate between a truely positive allergic reaction and an irritant reaction. What is the relevant patch test concentration of ascaridole?
First, to explore relationships between immunological factors (cytokines and chemokines), psychological stress, and pain, controlled for infection. Second, to explore relationships between immunological factors (MBL), bacterial colonisation and…
The main objective of this study is to assess perfusion of the foot and correlate perfusion values with arterial patency. To this end, first the PCT protocol of the foot in patients with CLI needs to be optimized in terms of contrast dose…
The primary objective is: The minimum time in days after treatment for Ng to perform a TOC using NAAT and DNA PCR. Secondary objectives are: Time to clearance per infected location. Host and pathogen related factors associated with time to clearance…
The study will be designed as a multicenter study to evaluate the impact of several parameters influencing the sensitivity and specificity of skin self tests.The parameters are:- Product applied: hair colouring formula mixed with developer (in use…
The aim is to validate the hypothesis that a positive history defined as dermatitis at exposure to a scented product and thereafter avoidance of such products in fragrance-hypersensitive individuals and a positive patch test result to fragrances is…
To investigate causes and predictors for primary or secondary allergy profiles for soymilk
The present research project is directed at delivering further evidence for the mechanisms underlying generalized and symptom-specific sensitization in patients with chronic pain and itching. For this purpose, 4 experiments are set up to provide…
Referring to the previous CMO approved research proposal (2004/222), in this study the effects of a short-term stressor and a stress-reducing intervention on neuroendocrine, immune and self-reported indicators of stress reactivity in patients with…
To test the feasibility of an intended large scale fragrance-allergy prevalence study in the population of the north of the Netherlands and to make a more reliable estimate of the prevalence in the population for poweranalysis of the intended large…