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Dutch south-West Psoriatic Arthritis Registry

In this study we will evaluate, what is the impact of *time to minimal disease activity* (MDA) on quality of life, work participation and radiographic joint damage at one and two year follow up in patients newly diagnosed with PsA.

Treatment of Skin Severity in Ichthyosis with Hyperbaric Oxygen Therapy

To assess clinical improvement of skin severity in patients with ichthyosis

Effectiveness of different strengths of topical steroids: providing evidence for a better treatment strategy in children with atopic dermatitis in general practice.

To determine whether a potent topical CS is more effective than a mild topical CS in the treatment of children with a moderate flare-up of atopic dermatitis in primary care on short and long term.

A Phase 3 Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Upadacitinib in Combination with Topical Corticosteroids in Adolescent and Adult Subjects with Moderate to Severe Atopic Dermatitis

This study has been transitioned to CTIS with ID 2022-502937-24-00 check the CTIS register for the current data. The objective of the study is to assess the efficacy and safety of upadacitinib combined with topical corticosteroids (TCS) for the…

A Multicenter, Randomized, Double-Blind, Secukinumab-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects with Moderate to Severe Chronic Plaque Psoriasis

Primary Objective:The primary objective of this study is to compare the efficacy of bimekizumab administered scfor 16 weeks versus secukinumab at achieving complete clearance (PASI100) in subjects withmoderate to severe chronic plaque PSO.The…

The UPDATE trial (Uvb Phototherapy in Dermatology for ATopic Eczema): A multicenter randomized controlled trial of narrowband UVB versus optimized topical therapy in patients with atopic eczema.

Comparing the effectiveness and cost-effectiveness of narrowband ultraviolet B with optimal topical therapy (NB-UVB+OTT) versus OTT at 3 months in adult patients with atopic eczema (AE).

The effect of the EMD protocol for urge compared to care as usual on dermatology-specific quality of life

Primary Objective: To assess the add-on effect of the EMD-U treatment compared to CAU, in improving dermatology-specific quality of life in patients with atopic dermatitis or prurigo nodularis who suffer from severe scratching behaviour. Hypothesis…

An Open-label Extension Study of ARGX-113-2009 to Evaluate the Long term Safety, Tolerability, and Efficacy of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid

This study has been transitioned to CTIS with ID 2024-515832-59-00 check the CTIS register for the current data. To assess the long-term safety and tolerability of treatment with efgartigimod PH20 SC in participants with BP

A Phase 3, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Safety and Efficacy of Baricitinib in Combination with Topical Corticosteroids in Adult Patients with Moderate-to-Severe Atopic Dermatitis Who Have Experienced Failure to Cyclosporine or Are Intolerant to, or Have Contraindication to, Cyclosporine

The primary objective is to test the hypothesis that baricitinib high dose level in combination with topical corticosteroids (TCS) or baricitinib medium dose level in combination with TCS is superior to placebo in combination with TCS in the…

The QWhet micro current wound stimulator, evaluation of efficacy and side effects

The aim of this study is to assess the effects and side effects of the QWhet micro current wound stimulation device in up to 78 subjects with a chronic wound over a continuous period of 28 days.The collected (coded) data will be used by Q Care to…

BioZ - study
Biologics during pregnancy
Immune profiling of peripheral and endometrial immune cells of women with psoriasis treated with biologics

To identify the effect of psoriasis and the treatment with biologics on the pre-pregnancy uterine immune environment of psoriasis patients.

Prevalence of fear of injections in patients with atopic dermatitis and the feasibility and acceptability of EMDR Flashforward in treating fear of injections in the dermatology outpatient clinic

Primary Objective: 1.1 To assess the prevalence of fear of injections in patients with atopic dermatitis1.2 To assess the prevalence of fear of injections in the partners of patients with atopic dermatitis, as a proxy for the age-matched general…

Treatment of chronic diabetic foot ulcers with Extracorporeal Shock Wave Therapy (ESWT) - a double-blind randomized controlled trial

To improve the healing rate and decrease wound surface area (WSA) of chronic diabetic foot ulcers using ESWT in combination with standard care. Furthermore, this study will investigate the long-term effects of ESWT on ulcer recurrence.

Clinical Study to Evaluate the Efficacy and Safety of Matrix Pro Treatment for Facial, Submental and Neck Laxity

Evaluate the efficacy and safety of the Matrix Pro Applicator on Profound Matrix system in the treatment of facial, submental and neck laxity.