12 results
To assess the effect of Caphosol® oral rinse on clinical outcomes of selected oral symptom burden (oral mucositis/stomatitis (aphthous-like), oral pain, taste change (dysgeusia), difficulty swallowing (dysphagia), difficulty oral intake, and dry…
Primary Objective: To determine whether topical application of rapamycin can lead to reduction in size and/or number of fibrofolliculomas in BHD patients and may prevent the growth of new ones. Secondary Objectives: Safety, formula acceptability and…
Primary objective: 1. To evaluate the effect of ustekinumab in patients with moderate to severe hidradenitis suppurativa (Hurley II-III), measured by disease specific score systmes: Sartorius/HS-LASI and PGA 2. To evaluate possible changes in scores…
To compare the efficacy of 7% lidocaine / 7% tetracaine cream and 2,5% lidocaine / 2,5% prilocaine cream in reducing self-reported pain during a single laser procedure in the treatment of acne keloidalis nuchae and tattoo removal.
The primary objective is to estimate the effect of spesolimab compared to placebo for the mean percent change from baseline in total abscessand inflammatory nodule count at Week 12. Secondary objectives are the evaluation of efficacy of spesolimab…
Therefore the primary objective of this study is to evaluate the effect of twice daily application of topical clindamycin1%/benzoyl peroxide 5% gel compared with the standard treatment with topical clindamycin1% lotion on the frequency of active…
To study the effect of local antifungal treatment of the toenails
The primary objective of this prospective study is to assess the clinical efficacy of the combination of adalimumab and surgery compared to adalimumab monotherapy after one year of treatment in adult patients with moderate to severe HS at the last…
To investigate the changes in the skin immune system after 12 weeks of biologic therapy treatment in patients with HS.
The primary objective of this study is to assess whether laser hair removal therapy improves the course and severity of mild to moderate HS, as assessed by the difference in IHS4 between groups over time between month 7 to month 12.
The primary objective of this study is to determine the clinical efficacy of doxycycline and metformin compared with the standard treatment with doxycycline alone after 24 weeks of treatment.
The primary objective of this trial is to assess the long-term safety of spesolimab in patients with HS who have completed the 1368-0052 PoCC trial and are qualified for entry into this trial. The secondary objectives are to evaluate efficacy at a…