19 results
Primary: to evaluate and compare the efficacy of:1) PDL treatment followed by topical sirolimus application after Er:Yag laser ablation of the stratum corneum in PWS 2) PDL treatment followed by topical sirolimus application without Er:Yag laser…
Determine the safety and efficacy of Tiscover compared to AS210 (acellular donor dermis, construct Tiscover is cultured on) for the treatment of chronic, therapy resistant (arterio-) veneus leg/foot ulcers in an out patient setting.
The primary objectives are:- To demonstrate the relationship of blood flow in the hands and the extent of digital ulcera in patients with systemic scleroderma;- Evaluate the effect of bosentan on the blood flow in the hands from baseline to 12 weeks…
To validate that OTR4120 will improve the healing of chronic ulcers.
The primary objective of the above study is to evaluate the wear time AQUACEL® Extra* when compared to AQUACEL® in subjects with venous leg ulcers. Stratification will be done for exudate (moderate vs highd) and type of dressing (AQUACEL®Extra*…
Primairy objective:- Evaluate the effect of bosentan on the blood flow in the hands from baseline to 12 weeks, measured by laser Doppler imaging, in SSc subjects with an early or active SSc pattern, measured with nailfold capillaroscopy (NFM), with…
To test whether the anatomical success rate of Steam Ablation is not inferior to that of EVLA in treatment of GSV insufficiency and compare the treatment related complications, patient reported outcomes and cost-effectiveness analyses between EVLA…
The objective of the study is to evaluate the clinical efficacy of 3M* Coban* 2 Layer Compression System in the treatment of venous leg ulcers compared to Rosidal® K shortstretch compression bandage (Lohmann & Rauscher, Rengsdorf, Germany).
The primary objective of this study is to assess the efficacyand safety of modifications of the laser treatment to increase the clearance of port wine stains.
Het wetenschappelijk onderzoek naar de meerwaarde van SW 112 op bacteriën/biofilm bij de behandeling van chronische voetulcera staat nog in haar kinderschoenen. Daarom is het doel van het onderhavige onderzoek om meer inzicht te krijgen in de…
Primary ObjectivesTo evaluate the IRE intensity/color mitigation effect of a single administration of Brimonidine tartrate in comparison with a vehicle gel (placebo).Secondary ObjectiveTo evaluate the IRE intensity/color mitigation effect of a…
To assess the relative effectiveness of HBOT as an adjunct to standard wound care in terms of preventing amputations and improving wound healing in ischemic diabetic ulcers, and its cost-effectiveness. Secondary objectives are to assess the patients…
5.1 Study hypothesisThe primary study hypothesis states that oral treatment with itraconazole will reduce the epistaxis severity score (ESS) due to the anti-angiogenic effects of itraconazole.5.2 Research question and primary outcomeWhat is the…
The primary objective is to evaluate and report the effect of an injected hyaluronic acid spacer on the rate of telangiectasia following PBSI.
The aim of this study is to evaluate the effect of psychological intervention on the quality of life and wound healing in patients with a foot ulcer.
Primary objective: Investigation of mean peak plantar pressure at the location of the diabetic foot ulcer and at 6 plantar regions of the foot (i.e. hallux, digits, first metatarsal, second to fifth metatarsals, midfoot, and heel) during total…
This study has been transitioned to CTIS with ID 2023-508530-34-00 check the CTIS register for the current data. Primary objective:* To demonstrate the efficacy of alpelisib as measured by the proportion of participants randomized to alpelisib with…
We do not currently have enough knowledge about the potentially beneficial effect that hyaluronidase might have on skin flap angiogenesis.
To demonstrate superior efficacy and non-inferior safety of the SELUTION SLR 014 DEB compared to PTA (uncoated balloon) in the treatment of peripheral arterial disease (PAD) in the BTK arteries in CLTI patients.