184 results
The primary objective is to set-up a well-defined sandwich ELISA method to measure the levels of Ara h6 in blood after peanut consumption.
The primary objective is to evaluate whether 2.5 µg VD3 analogue (Zemplar® * Abbvie) in multiple subcutaneously administered doses induces a more favourable (read: anti-inflammatory) systemic immune modulation both in general parameters and allergen…
To evaluate the efficacy and safety of a SCIT-treatment with a mutant recombinant fish-parvalbumin (mCyp c1) quantified in mass units and formulated in a solution with alum, in subjects with fish-allergy.
Primary Objective:Pilot study: Selection of the titanium derivatives which are capable of penetrating the skin, and thus can be used in the full study as patch test materials.Full study: To compare the results of three different diagnostic tests…
Primary Objective: Pilot study to identify the optimal patch test concentration for detecting contact allergy to ME-PPD in subjects with a proven contact allergy to PPD, who may be allergic to ME-PPD. Hypothesis: In this study subjects will be…
De objective of this study is to analyse the effect of exercise on the levels of Ara h6 in the blood after peanut consumption. Next to this we would like to know whether these levels found are in associated with the measure of intestinal…
Conditions that promote IL-10 producing B cells in humans are still ill defined. In this project our aim is to investigate the frequnecy of IL-10 producing B cells in healthy volunteers. Next, we aim to compare this to the frequency of IL-10…
Objective: The response over time on daytime alertness and performance will be assessed following a single oral dose of bilastine 20 mg in healthy volunteers performing flying ability tests in a hypobaric chamber with an ambient pressure of 75.2 kPa…
Primary objective: To evaluate the efficacy of dupilumab, compared with placebo, for reducing the use of maintenance oral corticosteroids (OCS) in patients with severe steroid-dependent asthma.Secondary objectives:To evaluate the safety and…
To determine the prevalence and severity of ASA-related allergic reaction in SM patients.
- Establashing the percentage of patients within a population allergic to house dust mite and/or crustaceans, that can get an allergic reaction from consuming mealworm.- Establashing the risk of sensitization and allergy by handling mealworms and…
Primary Objective:The primary objective of this study is to test the feasibility of methods and procedures prior to performance of a full-scale research project.Secondary Objective(s):The secondary objectives of this study are to determine whether…
To study the immunomodulatory effects of non-digestible oligosaccharides using peripheral blood mononucleated cells isolated from blood of healthy controls and patients with peanut or cow*s milk allergy.
The aim of this pilot study is to establish Th1/Th2/Th17 patterns in healthy controls by analysing cytokine concentrations in nasal fluid (nasal wash and cotton wool method), saliva and blood. This will be done in order to give an estimation about…
Primary: To characterize the QGE031 dose response relationship for the increase in the threshold dose of peanut protein that induces objective hypersensitivity reactions after treatment.Secondary (only key parameters): The percentage of patients…
Primary objective: To evaluate the efficacy of once daily doses of QAW039, as measured by EASI after 12 weeks of treatment, relative to placebo, in adult patients with moderate to severe AD. To evaluate safety and tolerability.Secondary objectives:…
The aim of the study is to identify patients with selective gamba-allergy and sensitization patterns for the various allergens in gamba extracts. Comparing sensitization patterns between patients who clinically react to Gamba with patients having a…
In this study we will compare the effect of intra nodal allegen injection with grass pollen to the intra nodal injection with placebo on symptome scores of allgic rhinitis (hay fever) in grass allergic patients.
To demonstrate that food elimination therapy based on component-resolved diagnostics is an effective and acceptable treatment for EoO patients.
Primary Objective: To determine minimum and non-provoking doses of soy protein (in mg) for soy allergic individuals Secondary Objective(s): To determine the relevant allergens of soy in soy allergy and to determine the relation between allergen…