8 results
Objective of this study is to provide evidence for the induction of AGEs in blood and tissue in patients with septic shock.
In previous studies we have identified specific receptor and surface protein expression profiles on neutrophils. Some of these profiles point at partially refractory neutrophils. In the current NERTHUS study we have seen that circulating neutrophils…
Exploring the incidence of fatigue after sarcoidosis, its severity and nature. Next we will try to associate fatigue with capacity to produce pro- and anti-inflammatory cytokines.Our secondary objective is testing the activity of the HPA-axis, the…
The general objective of this study is to elucidate the cellular components for HIV-1 infection in children.
Primary aimTo evaluate the effects of peginterferon and ribavirin therapy on the immune response in chronic HCV genotype 1 patients before, during and after treatment.Secondary aims1. To determine if differential modulation of Treg activity or DC…
Our purpose is to establish whether the frequently observed absence of tumor regression in the presence of infiltrating T lymphocytes is due to a lack of T cell effector function or due to an inhibitory influence of the tumor microenvironment on T…
To select T cell properties intrinsic to the transplant recipient, which can discriminate between patients who will likely experience acute cellular rejection episodes from those who don*t.
Research questions:Is the chronic inflammatory response in COPD caused by a dysfunction of regulatory T cells?1. Is the number of Tregs decreased in COPD?2. Is the function of the Tregs impaired in COPD? And if so,a. Is this associated with a…