207 results
Primary objectivesLongitudinal quantification of the total latent HIV reservoir with determination of the size of the replication competent HIV reservoir and investigate potential biomarkers of the HIV reservoir size and nature.Cross compare the…
To evaluate whether neuromuscular ultrasound discriminates between patients with and without ICU-AW.To detect differences between patients that do and do not have ICU-AW in order to determine relevant cut-offs which can be used in future diagnostic…
Primary objective: to assess the UCP-LF CAA test in travellers with high-risk water contact as compared to routine diagnostics
Primary objective:1. To evaluate the frequency of invasive fungal infections in a prospective pediatric oncology cohort and to identify the determinants of such invasive infections.2. Clinical validation of novel innovative diagnostic methods for…
To evaluate the role of white blood cell (WBC) scintigraphy in monitoring the response of infection treatment of a prosthetic joint infection.
To develop a novel multi-parametric diagnostic model for the management of patients with LRTI and/or sepsis that will be based on novel pathogen- and host-related factors.
The objectives of this study are: 1) To assess the user friendliness of the DBS self-sampling technique.2) To assess the quality of ssDBS.3) To estimate the agreement between viral loads in ssDBS and laboratory spotted DBS (labDBS).
To identify the most effective and safe long-term S. aureus carriage decolonization strategy in HPN patients. Ultimately this willlead to less antimicrobial resistance, less catheter removals and lower mortality rates. Also, other chronic…
To identify and quantify the HIV reservoir in T-cell subsets of patients who have been on ART for almost 20 years.
First, to explore relationships between immunological factors (cytokines and chemokines), psychological stress, and pain, controlled for infection. Second, to explore relationships between immunological factors (MBL), bacterial colonisation and…
Predicting fluid responsiveness during PLR and fluid challenge (FC) by changes in (Pms).
The aim of this study is to investigate immune response to pneumococcal vaccination in patients after community acquired pneumonia with S. pneumoniae compared to pneumonia patients with another pathogen.
To externally validate the accuracy of a host-response based diagnostics for differentiating between bacterial and viral etiology in pediatric patients aged 2 to 60 months with LRTI or FWS.
The primary objective of the study is to determine sensitivity, specificity, positive and negative predictive value of the enzyme analyses (myeloperoxidase, human neutrophil elastase and lysozyme) with wound biopsies as the gold standard.…
Primary: to determine the percentage of ILI attributable to influenza virus in elderly individuals * 60 years of age Secondary: to determine the relative contribution of influenza viral subtypesSecondary: to determine humoral and cellular immune…
This study aims to determine whether the ILC populations differ in the lungs of different phenotypes of asthmatic patients and healthy subjects and how these cells are regulated by bronchial epithelial cells. Furthermore we want to study how this is…
(i) to determine specificity of Q-detect* for registration purposes. (ii) to design a decision tree for follow-up of patients with a positive Q-detect* and
To determine the prevalence of HIV infection in patients presenting at the ED of the Erasmus MC, Maasstad Hospital or AMC
To assess short-term and long-term complications of mumps-associated orchitis in vaccinated men
To asess whether the Chlamydia Antibody Test (CAT), used to determine the presence of antichlamydia IgG antibodies in serum for diagnostics in the fertility clinic, can serve as an intermediate marker for PID/tubal pathology caused by Chlamydia.