254 results
Primary objective: Does a personalised behaviour intervention comprising of targeted in depth screening on mental health problems and drug use increase help seeking behaviour among MSM who are at high risk for STIs and HIV. Secondary objectives:…
1. To characterize long-term neurologic- and cognitive disorders, audiological and ophthalmological alterations in cCMV-infected children.2. To identify immunological, neurological host factors and virological factors that are predictive of…
1. Immunology and Pathology:To determine the immune response of patients with simple and complex appendicitis in order to identify markers which distinguish between simple and complex appendicitis.2.Clinical and Imaging:To analyze the differences in…
Analyse costs and effects of point of care (POC) C-reactive protein (CRP) measurement in children with non-severe lower respiratory tract infection (LRTI) in primary care.
The primary objective is to investigate quality of life after switch to a combination therapy including boosted DRV and DTG. Secondary objectives are to investigate 1) the residual viral replication, 2) level of virus production from infected cells…
Primary: to investigate the most importants determinants of the viral dynamics of low-level viremia. Secondary: to investigate the effects on immune activation, neurocognitive performance and periodontal status.
To estimate the incidence of S. aureus and P. aeruginosa ICU pneumonia, especially VAP, and to assess its association with patient-related and contextual factors, e.g. colonization status, serum antibody levels against S. aureus alpha toxin [AT],…
Objective of the study is to quantify the microbiological etiology in immunocompromised patients, at least 18 years of age, with CAP needing hospitalization. And to determine the severity, antibiotic use and outcome of CAP in immunocompromised…
The main objective is to investigate the additional value of CRP-POCT (C-reactive protein point-of-care-test) testing in patients suspected of airway infections in long-term care facilities.
To investigate the pathophysiological link between RA and PD, and test the efficacy of RvE1 treatment in gingival tissue biopsies of RA-PD and RA risk-PD patients ex vivo.
To characterize the interaction between the gut microbiome, related metabolites, immune function, and perceived complaints in QFS-patients, CFS-patients, and healthy individuals.
The primary objective of this study is to monitor changes in oral health during a 3.5-month naval mission and once one month thereafter.
determine the effect of cold exposure on influenza induced immune responses
The primary objective of the study is to assess the function and effect of deiodinase type 3 in PMN*s and the mechanisms behind its induction following activation of these cells.
The aim of this research is to contribute to the understanding of the pathophysiology of severe infections, and subsequently providee relevant new insights in the development of new treatment modalities. In the present research proposal we would…
This study's major aim is to determine whether a relation can be found between specific penile HPV types and the presence, quantity and size of flat penile lesions. Secondly, other possible determinants, such as HIV status, circumcision status…
The primary objective of this study is to explore if (and which) HIV-specific CTL responses shorten the lifespan of productively infected cells in HIV-infected individuals. This will be accomplished by investigating the estimated life spans of…
The overall aim of our study is to evaluate the management of suspected uncomplicated UTI in women presenting in primary care through use of a novel point of care test (POCT, Flexicult). This study is being carried out in 4 European networks: Wales…
To determine the frequency of MBL and FCN SNPs in patients with a history of a proven gram-positive bacteremia, compared to patients without such history. A secondary objective is to determine whether extracorporeal circuits, used in cardiothoracic…
The purpose of this study was to determine the incidence and severity of co-infection in children hospitalised for bronchiolitis, when cohorting of RSV-infected patients is omitted. . Furthermore we want to elucidate general epidemiological data on…