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Dientamoeba fragilis: clinical symptoms, optimal treatment and molecular detection

1. To determine clinical symptoms of Dientamoeba fragilis infection. 2. To evaluate the efficacy and safety of clioquinol versus metronidazol in the treatment of Dientamoeba fragilis in children.3. To evaluate the duration of positive PCR…

Prevalence of zoonotic protozoa in animal-keepers

Study of zoonotic protozoan infection in animal keepers. The findings will provide data which can be used to design better health polici for NHP and animal keepers.

Post travel screening
Screening for relevant parasitic infections in asymptomatic travellers returning from the tropics

To determine the usefulness of multiplex real-time pcr to detect asymptomatic parasitic infections in travellers returning from the tropics.

Optimizing parasite transmission to laboratory-reared mosquitoes following controlled human malaria infection with Plasmodium vivax asexual blood stage parasites in malaria-naïve healthy volunteers in the Netherlands

Main objective: Develop a protocol to reproducibly infect mosquitoes with blood from human study participants undergoing asexual blood stage CHMI with the P. vivax clone PvW1.Secondary objectives: Maximize mosquito infection rate with PvW1 by I)…

Long-term outcomes of pulmonary function in HIV-infected patients with a history of Pneumocystis jirovecii pneumonia

Assessing the prevalence of pulmonary function testing abnormalities in HIV-infected patients with and without a history of PJP.