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AN OPEN-LABEL, SINGLE-DOSE, SINGLE-PERIOD STUDY DESIGNED TO ASSESS THE MASS BALANCE RECOVERY, METABOLITE PROFILE AND METABOLITE IDENTIFICATION OF [14C]-OLOROFIM ADMINISTERED VIA THE ORAL ROUTE TO HEALTHY MALE SUBJECTS.

Approved WMORecruitment stopped

The purpose of this study is to investigate how quickly and to what extent olorofim is absorbed and eliminated from the body. Olorofim will be labelled with 14 Carbon (14C) and is thus radioactive. In this way olorofim can be traced in blood, urine…

Immunological Defects in Chronic Pulmonary Aspergillosis

Approved WMORecruiting

In this study, we aim to characterize the immunological defect in patients with CPA as compared to patients with chronic obstructive pulmonary disease (COPD) without CPA on a functional, genetic, transcriptional and metabolic level.