80 results
Primary objectivesLongitudinal quantification of the total latent HIV reservoir with determination of the size of the replication competent HIV reservoir and investigate potential biomarkers of the HIV reservoir size and nature.Cross compare the…
The objectives of this study are: 1) To assess the user friendliness of the DBS self-sampling technique.2) To assess the quality of ssDBS.3) To estimate the agreement between viral loads in ssDBS and laboratory spotted DBS (labDBS).
To identify and quantify the HIV reservoir in T-cell subsets of patients who have been on ART for almost 20 years.
To externally validate the accuracy of a host-response based diagnostics for differentiating between bacterial and viral etiology in pediatric patients aged 2 to 60 months with LRTI or FWS.
Primary: to determine the percentage of ILI attributable to influenza virus in elderly individuals * 60 years of age Secondary: to determine the relative contribution of influenza viral subtypesSecondary: to determine humoral and cellular immune…
This study aims to determine whether the ILC populations differ in the lungs of different phenotypes of asthmatic patients and healthy subjects and how these cells are regulated by bronchial epithelial cells. Furthermore we want to study how this is…
To determine the prevalence of HIV infection in patients presenting at the ED of the Erasmus MC, Maasstad Hospital or AMC
To assess short-term and long-term complications of mumps-associated orchitis in vaccinated men
The primary objective is to explore the association between peripheral T-cell activation and apoptosis and hepatic fibrosis in various underlying liver diseases. Secondary objectives are 1) to investigate whether level of T cell activation and…
To examine neurocognition in 100 HIV1 seropositive patients on chronic effective cART using three different tests: the Montreal cognitive assessment (MoCA) , the International Aids Dementia scale (ADS) and extensive neuropsychological testing of…
Applicability of fetal brain imaging techniques for clinical purposes.
The aim of the research is to gain more knowledge on the influence upper respiratory infections on the course of pregnancies.
Primary: to determine the percentage of ILI attributable to influenza virus in elderly individuals >= 60 years of age Secondary: to determine the relative contribution of influenza viral subtypesSecondary: to determine humoral immune response…
• Our purpose is to prospectively characterize influenza infections over a 3 year period in transplant patients using a registry system.• We plan to generate robust data on clinical features of upper and lower respiratory disease, antiviral therapy…
The main objective of this study is to compare DTI findings of PPS patients with those of healthy controls. Secondary objective of this study is to correlate DTI findings with clinical data such as isometric muscle strength. Third objective is to…
The main objective is to study the impact of cross-reactivity by other flaviviridae (Yellow Fever virus, Tick Born Encephalitis virus, West Nile virus, Japanese Encephalitis virus and Hepatitis C virus) on Dengue IgG serology using enzyme-linked…
The objective of this study is to gain insight into the occurence of mumps in a, presumed, highly immune student population, both clinical and subclinical mumps. Furthermore, there shall be an attempt to calculate the 'correlate for protection…
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Technical validation of HIV antibody detection in capillairy blood sampled with the Demecal set.
Primary objectives:(1) To describe the incidence of EV and HPeV infections in Dutch children(2) To determine the major symptoms of EV/HPeV infections in children(3) To evaluate the epidemiology and symptoms of the different subtypes of EV and HPeV(4…