7 results
Primary objective: to assess the UCP-LF CAA test in travellers with high-risk water contact as compared to routine diagnostics
The objective of the standardized protocol is optimalizing the accuracy of the diagnosis (all-cause pneumonia, or serotype-specific pneumonia) during the 13-valent pneumococcal vaccin (13vPnC) study which will be performed in 2008. Additionaly, the…
To differentiate between gene expression in sepsis and sterile sirs.
Primary Objectives: - To determine the protective efficacy of repeated exposure to male Schistosoma mansoni (Sm) cercariae in healthy Schistosome-naïve volunteers based on CAA levels.- To determine the safety and tolerability of repeated exposure to…
To determine the proportion of travelers and migrants diagnosed with chronic schistosomiasis as per each centre*s routine assessment, who have active infection at presentation (as assessed and classified by composite reference standards integrating…
Primary objective:* To determine the safety and tolerability of repeated infection of Necator americanus L3 larvae in healthy volunteersSecondary objectives:* To compare the variability in egg output after cumulative infection with 50, 100 and 150…
Primary objective:* To determine the protective efficacy of repeated short term exposure to hookworm infection Secondary objectives:1. To explore the immunological response after repeated hookworm infections2. To evaluate the safety of and number of…