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Paracetamol or NSAID's in acute musculoskeletal syndromes

The objective of the current study is to compare three different strategies of pain management in patients presenting to an emergency department and to a general practice with acute musculoskeletal syndromes (defined as musculoskeletal complaints…

The analgesic efficacy of Δ9-THC (Namisol®) in patients with persistent postsurgical abdominal pain: a randomized, double-blinded, placebo-controlled, parallel design

Primary Objective: - To investigate the analgesic efficacy of a stable dose Namisol® in patients suffering from persistent postsurgical abdominal pain. Secondary Objectives:- To investigate the effect of a stable dose Namisol® on central nervous…

OTR4120: topical application to split-skin graft donor sites. A clinical evaluation on the healing.

Objective: To demonstrate the efficacy of a novel matrix therapy based technology that creates improved wound healing in a clinical donor site model.

Driving under the influence of Drugs, Alcohol and Medicines
Effects of dexamphetamine with and without alcohol on simulated driving

To assess the effects of dexamphetamine with and without alcohol on simulated driving performance.

Cosmo-Niveau
"Cosmetic results of choosing a different level of skin- and fascia-incision in a low transverse abdominal incision"

To determine whether there is any difference in the cosmetic result among women undergoing surgery for gynaecological diseases using two different lower transverse abdominal incisions: the Pfannenstiel incision versus a comparable technique in which…

Complement Inhibition: Attacking the Overshooting Inflammation @fter Traumatic Brain Injury ( A phase II trial on the safety and efficacy of C1 esterase inhibitor Cinryze for the acute management of severe traumatic brain injury)

This study has been transitioned to CTIS with ID 2024-514488-24-01 check the CTIS register for the current data. Primary Objective: To determine the safety and efficacy of 6000 IU Cinryze in patients with moderate and severe TBI (GCS <13 with…

A comparison of pericapsular nerve group block, fascia-iliaca compartment block and femoral nerve block for pain management in patients with hip fracture in the emergency department - A randomized controlled trial

The aim of this study is to compare the efficacy and safety of preoperatively placed Pericapsular Nerve Group block (PENG), Fascia-Iliaca Compartment Block (FICB) and Femoral Nerve Block (FNB) for patients with hip fractures in the ED.

MORphine use in the Fascia Iliaca Compartment block with UltraSound

The main study endpoint will be the mean preoperative morphine use per hour in patients with and without FICB with levobupivacaine, guided by ultrasound. Secondary parameters will include the pain scores reported by the numerical rating scale both…

CE marking for the Q-whet micro current wound stimulator

Objective:The objective of the study is to test the hypothesis that the QWHET micro current wound stimulation device has minimal side effects. The study will be designed as a double blind, prospective study.The results will be used to obtain a CE…

Femoral Nerve Blockage in Proximal Femoral Fractures in patients of 65 years of age or older, a Randomised Controlled Trial

The objective of this study is to determine the clinical outcomes of ultrasound guided femoral nerve blockage using intermitting shots of levobupivacaine, in patients with hip fractures and to compare these results with placebo injections.The…