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A multicenter, multinational, randomized, controlled, open label study, performed in children with thermal burns, to evaluate the efficacy and safety of NexoBrid as compared to standard of care (SOC) treatment

To evaluate the safety and clinical benefit of NexoBrid in hospitalized children (0-18 years) with deep partial and/or full thickness thermal burns of 1-30% TBSA and to compare NexoBrid to standard of care (SOC).

The effect of Caphosol on the development of esophagitis in (N)SCLC patients treated with concurrent chemo/radiotherapy

Trial hypothesisAdding the use of Caphosol® (rinsing and swallowing four times a day) to the standard of care for esophagitis/mucositis, reduces the incidence, onset, duration and severity of esophagitis in (N)SCLC patients, comparing to the…

OTR4120: topical application to split-skin graft donor sites. A clinical evaluation on the healing.

Objective: To demonstrate the efficacy of a novel matrix therapy based technology that creates improved wound healing in a clinical donor site model.

*Pain exposure* physical therapy versus standard therapy for patients with complex regional pain syndrome type 1 (CRPS-1)

Despite a lacking scientific argumentation, the PEPT approach or Macedonian therapy, is now being adopted on a large scale among physical therapists in The Netherlands for patients with CRPS-1. There are two level C retrospective cohort studies…

The effect of Virtual Reality on pulmonary recovery and mobility in patients with blunt chest trauma.

Primary Objective:To investigate the effect of respiratory and physical exercises in VR on pulmonary recovery compared to the standard of care of patients suffering from blunt chest trauma.Secondary Objective(s):- To investigate if VRx can improve…