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Wrist repair in severe trauma (WRIST) study

The objective of this study is to investigate whether reconstruction of the radiocarpal joint by implantation of a tailor-made and patient specific 3D printed interpositional arthroplasty made out of Bionate® II 80A PCU (DSM®) is feasible as a…

Paediatric distal radius torus fracture treatment comparison in a prospective randomized control trial: mitella versus plaster cast

If the study shows that the treatment with a sling gives an earlier return to normal function en does not give a clinically significant difference in pain experience compared to cast therapy than the traditional treatment can be adjusted. We aim at…

Multi-Center Evaluation of Post-Operative Recovery in ATTUNE Primary, Cemented Total Knee Arthroplasty

The primary objective of this study is to determine the rate of recovery of the ATTUNE knee from the time of surgery at the 6 month endpoint.

A multicenter, multinational, randomized, controlled, open label study, performed in children with thermal burns, to evaluate the efficacy and safety of NexoBrid as compared to standard of care (SOC) treatment

To evaluate the safety and clinical benefit of NexoBrid in hospitalized children (0-18 years) with deep partial and/or full thickness thermal burns of 1-30% TBSA and to compare NexoBrid to standard of care (SOC).

Evaluation of different wound dressings in the treatment of children with spoke injuries

To study wether a biodressing impregnated with polyhexamethylene biguanide in the treatment of spoke injuries in children could give a reduction in pain during the treatment compared to the standard treatment with wound dressing impregnated with

Gait Analysis after Internal Fixation for a Femoral Neck Fracture

Primary objective:To assess the effect of implant choice (CS vs SHS) on gait pattern in patients that are >1 year after surgical treatment for a femoral neck fracture.Secondary objectives1. To assess the effect of implant choice (CS vs SHS)…

Improving partial weight bearing compliance of patients after lower limb surgery using an auditory feedback device: a feasibility study

Primary Objective: To determine whether it is feasible to use an ABF device to lower the amount of steps that exceed the maximum allowed force.The specific research question that the study aims to answer is:- Is it possible to increase partial…

Clinical Application of a Dermal Substitute based on glycerol
preserved Allograft: GLYADERM®
A multicentre, prospective, controlled, randomized, comparative
trial of Glyaderm® and split thickness skin graft versus split
thickness skin graft alone in full thickness skin defects

Objective: The main objective is to evaluate the difference in scar quality, after skin restoration of full thickness defects treated with Glyaderm® and STSG versus STSG alone.Secondary objectives are: to evaluate the percentage of Glyaderm® take…

*Unilateral fracture of the mandible: a comparison of intermaxillary fixation with screws or arch bar*

The aim of the present study is to demonstrate the effectiveness of screw IMF.

Four-part fractures of the proximal humerus; conservative treatment or reversed type shoulder prosthesis

Our primary objective is to compare the short-term (one-year follow-up) clinical results of the DePuy Delta Xtend reversed shoulder prosthesis with conservative treatment, in the management of displaced four-part fractures of the proximal humerus of…

Prospective feasibility, non-randomized, single arm multicentre, multinational interventional clinical investigation using INSTRUCT therapy for the repair of knee cartilage defects.

This pilot clinical trial has been designed to evaluate the safety and performance of the INSTRUCT scaffold, and to collect preliminary efficacy data

Potential Carcinogenic Effects of Endovenous Laser Ablation

This study will determine the concentration of benzo[a]pyrene before and after EVLA.

Paracetamol or NSAID's in acute musculoskeletal syndromes

The objective of the current study is to compare three different strategies of pain management in patients presenting to an emergency department and to a general practice with acute musculoskeletal syndromes (defined as musculoskeletal complaints…

Pediatric Analgesia via the Intra-Nasal route. An observational multicenter prospective cohort study of atomized intranasal fentanyl in pediatric trauma patients in the emergency department

Primary objective:Our primary objective is to determine if the intranasal (IN) route is an effective, safe and quick alternative for intravenous fentanyl to treat acute pain in emergency department pediatric traumapatients. Secondary objectives:To…

Traumatic Splenic Injury and Management
"Quality of Life and Clinical Outcomes of Treatment for Splenic Injury after Trauma"
Retrospective study

The primary objective of this project is to demonstrate the equivalence of treatment of traumatic splenic injury with splenic artery embolization (SAE) compared to splenectomy and non-operative management (NOM) in terms of quality of life measured…

Play with the IROMEC robot during rehabilitation and special education for children with severe physical disabilities - an explorative feasibility study.

This study aims to examine the feasibility and an indication of possible effects of an IROMEC robot based play therapy within rehabilitation and special education on the level of playfulness of children with severe physical disabilities.

A multicenter randomized controlled trial comparing long term scar quality after hydrosurgical versus conventional tangential excision of deep dermal burns

To assess and compare long term scar quality of deep dermal burns after debridement with hydrosurgical- and conventional tangential excision.

Initial results of the Anser: A novel intramedullary device for fixation of midshaft clavicle fractures.
An explorative case series

The goals of this study are to evaluate the initial performance, safety and functional results of the Anser; A novel intramedullary device for fixation of midshaft clavicle fractures. The primary outcome measures will be union rate, complication…

Local gentamicin in Redon treated post-sternotomy mediastinitis

The aim of our study is to evaluate clinical outcomes of patients primarily closed over Redon catheters for the treatment of PSM, comparing the application of local gentamicin with a control group.

Use of the Auditory Biofeedback system to improve a patient*s partial weight bearing compliance: a feasibility study

Primary Objective: To determine whether it is feasible to use an ABF device to lower the amount of incorrect steps. Incorrect steps are the steps exceeding the maximum allowed load or being below the minimum load.The specific research question that…