165 results
The objective of our observational clinical trial is to quantify the apoptosisrates of fibroblasts and growth-factorchanges in hypertrophic (burn) scars treated with pressure and/or silicone therapy.
To test the hypothesis stated above, we propose to study the dose-response relationship between various chemostimulants and PMN functions of major trauma patients and patients undergoing major surgery in vitro, both early after the initial trauma or…
Despite a lacking scientific argumentation, the PEPT approach or Macedonian therapy, is now being adopted on a large scale among physical therapists in The Netherlands for patients with CRPS-1. There are two level C retrospective cohort studies…
To assess the effects of dexamphetamine with and without alcohol on simulated driving performance.
The primary study objective is to investigate the contribution of peri-operative suppletion of bile to the preservation of bodyweight (expressed in kilograms).Secondary study objectives:1.To determine the contribution of peri-operative suppletion of…
In this study the differences in variability and stability of people walking with and without a limb prosthesis will be investigated. In addition, it will be studied which of the employed outcome measures will discriminate best between both groups.…
We hypothesize that ultrasound visualization of the distal sciatic nerve with subsequent ultrasound guided injection of a reduced amount of local anesthetic will result in shorter performance times, equivalent block quality (sensory and motor onset…
To determine if patients with sub-clinical lengthening of coagulation test, low platelets or use of Ascal have increased risk of clinical significant bleeding during and after tracheotomy.
The objective of this study is to prove that chronic post-sternotomy pain is not a local painproblem, but part of a general painsyndrom.Our hypothesis is twofold:1. The investigated painsymptoms are of more frequently occurrence in the pain-sample…
To determine whether there is any difference in the cosmetic result among women undergoing surgery for gynaecological diseases using two different lower transverse abdominal incisions: the Pfannenstiel incision versus a comparable technique in which…
To investigate whether application of Steri-Strip* S will lead to: 1) shorter treating time 2) improved satisfaction with the patient 3) improved wound healing4) improved cost-efficiency5) improved satisfaction with the attendant
The current study aims to gain better insight into the pathophysiology of the aberrant inflammatory response in CRPS. The evaluation of the role of pro-inflammatory and anti-inflammatory mediators in response to a microtrauma may generate important…
The primary aim of the proposed multi-site study will be to determine internal and external validity of the proposed new diagnostic criteria.
This study will give an insight in the incidence of cold intolerance of patients with a fracture of the hand. This study will also show if there is a relation between the rewarmingpattern and the cold intolerance of patients with a hand fracture.
The primary goal is investigating the number of women that have lymphedema five years after the treatment for breast cancer. In the describing part of this study, the focus will be on the correlation between lymphedema and 1) surgical treatment, 2)…
The main objective of this multicentre interdisciplinary study is to systematically aggregate data on moderate and severe traumatic brain injury patients in a national database. This database will serve to:a. get an estimation of the incidence of…
Aim of this study is to investigate the level of functioning and the quality of life of children and young adults, six to eight years after major trauma.
The following questions will be answered:• Can typical protein-profiles in a proteomic-assay be identified after trauma, which might be correlated with the outcome of the patients?• How is the dynamic of protein-profile-changes in the proteomics-…
Determining the sensitivity and specificity of the on-site GHB test.
The primary objective of this project is to demonstrate the equivalence of treatment of traumatic splenic injury with splenic artery embolization (SAE) compared to splenectomy and non-operative management (NOM) in terms of quality of life measured…