Search for a trial

A multicenter randomized controlled trial comparing long term scar quality after hydrosurgical versus conventional tangential excision of deep dermal burns

To assess and compare long term scar quality of deep dermal burns after debridement with hydrosurgical- and conventional tangential excision.

Evaluation of different wound dressings in the treatment of children with spoke injuries

To study wether a biodressing impregnated with polyhexamethylene biguanide in the treatment of spoke injuries in children could give a reduction in pain during the treatment compared to the standard treatment with wound dressing impregnated with

Biomarkers for soft tissue damage in a rigid and a soft-layered spineboard

In this study we want to investigate if there are differences in cytokine and mFABp production when using a rigid and a soft-layered spineboard, in relation to tissue-interface pressures. Furthermore, redness of the skin and experienced comfort are…

Clinical Application of a Dermal Substitute based on glycerol
preserved Allograft: GLYADERM®
A multicentre, prospective, controlled, randomized, comparative
trial of Glyaderm® and split thickness skin graft versus split
thickness skin graft alone in full thickness skin defects

Objective: The main objective is to evaluate the difference in scar quality, after skin restoration of full thickness defects treated with Glyaderm® and STSG versus STSG alone.Secondary objectives are: to evaluate the percentage of Glyaderm® take…

Functional outcome after skin grafting of the burned dorsal hand in fist position with wrist in 30° flexion: evaluation of a new treatment protocol

1. To assess the feasibility of a new treatment protocol of skin grafting of the burned dorsal hand in fist position with wrist in 30° flexion per and post ok.2. To explore the effects of skin grafting on the burned dorsal hand in fist position with…

Traumatic Splenic Injury and Management
"Quality of Life and Clinical Outcomes of Treatment for Splenic Injury after Trauma"
Retrospective study

The primary objective of this project is to demonstrate the equivalence of treatment of traumatic splenic injury with splenic artery embolization (SAE) compared to splenectomy and non-operative management (NOM) in terms of quality of life measured…

Complement Inhibition: Attacking the Overshooting Inflammation @fter Traumatic Brain Injury ( A phase II trial on the safety and efficacy of C1 esterase inhibitor Cinryze for the acute management of severe traumatic brain injury)

This study has been transitioned to CTIS with ID 2024-514488-24-01 check the CTIS register for the current data. Primary Objective: To determine the safety and efficacy of 6000 IU Cinryze in patients with moderate and severe TBI (GCS <13 with…

Comparing Restrictive vs. Liberal Oxygen Strategies for Trauma Patients: The TRAUMOX2 Trial

The main aim is to compare the effect of a restrictive versus liberal oxygen strategy the first eight hours after trauma on the incidence of 30-day mortality and/or major respiratory complications (pneumonia and ARDS) within 30 days (combined…

The effect of Virtual Reality on pulmonary recovery and mobility in patients with blunt chest trauma.

Primary Objective:To investigate the effect of respiratory and physical exercises in VR on pulmonary recovery compared to the standard of care of patients suffering from blunt chest trauma.Secondary Objective(s):- To investigate if VRx can improve…

Traumatic Splenic Injury and Management
"Quality of Life and Clinical Outcomes of Treatment for Splenic Injury after Trauma"
Prospective study

The primary objective of this project is to demonstrate the equivalence of treatment of traumatic splenic injury with splenic artery embolization (SAE) compared to splenectomy and non-operative management (NOM) in terms of quality of life at…