23 results
The aim of this study is to compare the new (covered) TIPS stent with the standard treatment, local band ligation and/or sclerosing of the bleeding vessel under endoscopic guidance, in patients with acute bleeding of esophageal varices, with regard…
The objective of the study is to improve quality of life of patients with Hepatitis C, by teaching patients psychological skills that aid in coping with the consequences of the disease.
To evaluate the use of concentration-controlled everolimus, with the reduction or the elimination of tacrolimus, to provide superior renal function and to provide non-inferior rates of the composite efficacy endpoint compared to the tacrolimus…
Determine if maximum doses of atorvastatin are safe in patients infected with chronic hepatitis C and if the so called pleiotropic effects of atorvastatin cause a decrease in the HCV viral load.
efficacy of lanreotide LAR in controling total liver volume in patients with hepatic cysts as a result of ADPKD or PCLD
To study the correlation between histology and elastography in patients with elevated liver enzymes more than two times normal upper limit and the suspection of liver fibrosis or cirrhosis treated with MTX from the department Rheumatology and…
The aim of this study is to compare the new covered TIPS-stent with paracentesis with albumin infusion with regard to nutritional status, quality of life and survival. The theory is that when ascites is treated in an earlier stage of liver cirrhosis…
To show whether an intake of 20g CLA per day has negative effects on liver and kidney function in healthy human volunteers.
Primary objectives : to investigate the safety and tolerability of multiple oral doses of JTK-652 administered for 14 days to healthy male subjectsSecondary objectives : tot determine the pharmacokinetics of multiple oral doses of JTK-652…
The aim of this study is: 1) to determine the burden of ERCP in patients undergoing ERCP (descriptive study) and 2) to determine patients preferences for treatment strategy of CBDS (Discrete Choice Experiments).
Evaluation of quality of life and resoration of function after bile duct injury.
Validation and quantification of 3.0 Tesla 1H *MRS for the assessment of hepatic steatosis in patients with non alcoholic fatty liver disease and patients chronically infected with hepatitis C. Is there a close correlation between the 1H *MRS…
Assessment of intra en inter reproducibility of 3.0 Tesla proton magnetic resonance spectroscopy in assessing hepatic steatosis. Reproducibility of visible peaks in water unsuppressed and suppressed MR spectra.
Primary Objective:Validate the accuracy of:· MR Flow mapping in measuring PPG in patients with GoreTex®-covered TIPS as compared to the gold standard, portography.· MRA for establishing TIPS patency as compared to Doppler US and using invasive…
To investigate feasibility, safety, and effectiveness of covered expandable stents with a proximal lasso to resolve benign post-surgical strictures.
The primary objectives of this trial are the following:- to determine the dose dependency of the antiviral effect of TMC435350 during 1 week ofmonotherapy in treatment-naïve HCV-infected subjects;- to determine the dose dependency of the antiviral…
To assess the bile acid composition of cystic bile and serum pharmacokinetics after a 3-week treatment with UDCA and to correlate pharmacokinetic parameter sof UDCA in bile and serum during steady state.To compare the composition of bile acids and…
The aim of this study is to validate a protocol for ultrasonographic hepatic fat assessment, by means of Magnetic Resonance Imaging technique (MRI) as gold standard.
- Is there a correlation between liver fat content and inflammation in patients with or without STNFR-2 polymorphisms (-1031C, -863A)?- What is the correlation between weight reduction and decrease of hepatic steatosis?- What is the correlation…
Validation of pre-operative H1-MRS at 3.0 Tesla for assessment of hepatic steatosis as a risk factor for postoperative morbidity and mortality after hepatectomy. Is there a close correlation between the 1H -MRS measurement of fat and the…