52 results
To demonstrate that the infliximab serum concentration of Remsima* is non-inferior to the infliximab serum concentration of Remicade , 16 weeks after switch from Remicade to Remsima* in subjects with CD, UC or RA in stable remission for > 30…
Primary Objective: To assess the impact of RYGB on gallbladder function (during a follow-up interval of 1 year). We will assess the fasting volume, the ejection fraction and the residual volume of the gallbladder. In addition, we will compare serum…
To compare the efficacy of a fixed dose of SC methylnaltrexone to induce laxation in patients receiving palliative care with constipation due to either fentanyl, oxycodone or morphine sulphate (opioids with different mechanisms of action). Secondary…
The goal of this study is to compare the efficacy and safety of the Wallflex stent to the Egis stent.
To assess the safety of lengthening the adalimumab dosing interval from 2 to 3 weeks, in patients with Crohn*s disease or ulcerative colitis in long term (6 months) remission.
To identify what might be the cause of the occurrence of diarrhea during the use of angiogenesis inhibitors sunitinib and sorafenib in patients with a malignancy.
Primary objectives1. What is the effect of stopping mesalazine in the maintenance setting of patients with quiescent CD?2. Can subgroups of CD patients, for example based on prior treatment (medical vs. surgical), localization of disease, disease…
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The study is designed to assess the diagnostic value of contrast agents on endosonographic images during the evaluation of focal pancreatic lesions.
Evaluation of the effectiveness of a new system HD2/NBI2 to improve the detection of colorectal neoplastic lesions during colonoscopy in comparison to the former generation with currently highest share of the installed base (nonHD-nonNBI system i.e…
To determine the percentage of patients with nodular regenerative hyperplasia of the liver after at least 1 year of combination therapy of allopurinol and low dose AZA or MP and to compare this with the reported findings of 6TG induced NRH
The primary objective of the study is to prospectively determine whether fluoropyrimidine-induced toxicity is preventable by dose adjustment prior to start of the first administration based on the polymorphic status of the DPYD*2A polymorphism in…
To study the influence of omeprazole and pantoprazole on the platelet reactivity index and the inhibition of platelet aggregation by clopidogrel.
Effectiveness of treatment with clioquinol on parasitologic eradication is being studied as well as the clinical effectiveness of eradication in children with dientamoeba fragilis infection.
To determine the efficacy and tolerability of L-Autogel in patients with early or late dumping syndrome after gastric surgery.
To establish the preferred treatment of AIN to prevent the development of severe anal neoplasia (persistent AIN III or anal carcinoma) in HIV+ MSM and HIV+ woman.
The primary goal of the study is the prevalence of NRH in patients with IBD, who have been treated for at least five years with azathioprin or 6-mercaptopurin. A MRI of the liver, using the Seiderer protocol, and a percutaneous liver biopsy will be…
The objective of this study is to assess the association of genetic polymorphisms known to be involved in coeliac disease with specific clinical phenotypes in coeliac disease.
This study aims to investigate the reaction of the peri-implant tissues to these materials when used in oral implant dentistry.