36 results
The aim of this prospective study is 1) to evaluate the diagnostic efficacy of DBE in comparison to MRE as surveillance technique of the small-bowel in PJS patients, 2) to analyze patient burden and quality of life with DBE and MRE, and 3) to…
This study aims to assess the efficacy, safety and effectiveness of LumenR-assisted ESD for the treatment of large rectal adenomas. In addition, the learning curve for this technique in endoscopists with experience in standard ESD is assessed.
To prospectively validate the SERT scoring system for adenoma recurrence rates around the EMR scar after WF-EMR with SCAR technique applied to the defect margin.
The primary objective of this study is to determine the sensitivity of the fluorescent tracer bevacizumab-IRDye800CW using a NIR fluorescence endoscope ans spectroscopy probe in identifying adenomatous polyps during surveillance endoscopy in…
Primary Objective: To identify variants in the humane genome that are associated with BE risk. Secondary Objective(s): We will collect information on BE length, complication of BE (dysplasia, ulcer, stricture or EAC), presence of esophagitis and…
To compare the percentage of incompletely resected polyps during colonoscopy for polyps sized 1-4 mm, 5-9 or 10-20 mm.
The main goals of this study1) To determine the prevalence of BE among first degree relatives of index patients in families that fulfil criteria for familial BE/adenocarcinoma of the GEJ2) Collect tissues of the index patients and all first degree…
To establish the safety and preliminary efficacy of Check-Cap*s P1 Capsule System in patients eligible for CRC screening
The primary objective is to generate genome-wide miRNA profiles of patient material (tissue samples and blood). The secondary objectives are to compare miRNA expression profiles to investigate what role differences in miRNA expression have in the…
Study the risk of colorectal adenomas in patients detected with duodenal adenomas.
1. To determine the prevalence of gastric fundic gland polyps in patients undergoing routine upper gastrointestinal endoscopy2. To determine the prevalence of dysplasia in these gastric fundic gland polyps3. To determine the prevalence of gastritis…
The SuMO System showed good results for mucosal resection in a porcine model. This study is developed to evaluate the feasibility and safety of the SuMO (submucosal operation) Access and Tissue Resection System in human colon and rectum tissue.
Objective: Two issues will be addressed:i) does pan-colonic chromoendoscopy improve the diagnostic yield of colonic polyps (and in particular flat lesions) as compared to conventional colonoscopy?ii) does pan-colonic chomoendoscopy combined with…
In a randomized trial we will compare the cost-effectiveness and cost-utility of TEM and EMR for the resection of large rectal adenomas.
In the present study the effects of the colonic administration of butyrate on portal, hepatic, mesenteric venous and arterial SCFA concentrations will be studied in patients undergoing major upper abdominal surgery. The aim is to clarify the…
To assess the skeletal health of FAP patients.
To compare the sensitivity and specificity of MR colongraphy with that of CT colonography for the detection of colonic neoplasms, compared to colonoscopy as "gold standard".
The aim of this study is to compare the additional diagnostic yield (adenoma detection rate) of G-EYE colonoscopy with that of standard high definition colonoscopy.
Identify DNA methylation markers suitable for sensitive and specific plasma-based detection of advanced colorectal adenomas.
Lynch-related tumors mostly develop in the ascending right side of the colon (70-85%). Strikingly, it was recently discovered that dense bacterial biofilms and invasive bacteria occur in the colonic mucosa of 87% of right-sided colorectal cancer (…