Search for a trial

Comparison of Cousin Biotech® Adhesix* versus conventional mesh in open anterior inguinal hernia repair: a Multi-centre, Randomised, Double-blinded, Controlled Clinical Trial.

We would like to conduct a multicentre randomised controlled clinical trial to compare the difference in early postoperative pain after unilateral primary inguinal hernia repair in males. The procedures will be performed in day surgery. Early…

Reinforcement of closure of stoma site

To assess whether a biological mesh (collagen tissue matrix) reduces the incidence of clinically detectable stoma closure site hernias at two years compared to standard closure techniques.

Recurrence rate of hiatal hernia repair with biomesh compared to repair without mesh * a double blinded, randomized, controlled trial.

The above mentioned literature shows that repair of a hiatal hernia using a mesh gives fewer recurrences than repair without mesh. However, there are few prospective randomized controlled trials that provide clear results about this. The most…

A Multicenter, Prospective, Single-Blind, Randomized, Controlled, Study of the Repair of Challenging Abdominal Wall Defects: Strattice TM in abdominal Wall Repair (StaR)

The primary objective of this clinical study is to compare the incidence of post-repair wound related complications, including hernia occurence/reccurence between challenging abdominal wall defects repaired with Strattice Reconstructive Tissue…

Prevention of Parastomal Hernias and Incisional Hernias in Old Stoma Wounds: a pilot Study

We would like to conduct a RCT to confirm the hernia prevention effect of a mesh, however in a slightly different position, with a different mesh and with all types of stomas. In addition, we want to measure the possible benefit in terms of quality…

Prevent Trial;Prevention of parastomal hernia during construction of a colostomy by reinforcing the bowel wall with a polypropylene mesh. ;A multicentre randomized controlled trial.

Patients in whom a permanent (end) colostomy is created in (semi) elective setting are randomised between the placement of a polypropylene mesh during stoma creation and the classic method without a mesh. Primary aim: Does the use of a lightweight…

PREventing Surgical Site occurrences using negative pressURE wound therapy

Primary Objective: Primary objective of this trial will be to determine whether iNPWT reduces the number of patients with clinically relevant* SSOs after (potentially) contaminated ventral hernia repair <30 days after surgery. *A SSO is…

MARS study- Mesh Augmented Reinforcement of Abdominal Wall Suture Line in Patients Undergoing Midline Laparotomy to limit the Rate of Incisional Hernia ( IH) Occurrence

The purpose of this prospective, pivotal, multi-center, single-arm cohort, pre-market, investigational clinical study is to assess the safety and performance of Deternia* Self-Gripping Resorbable Mesh when used for suture line reinforcement after…

Randomized Controlled Trial of Laparoscopic Primary Diaphragm Repair with Sutures Alone versus Sutures Reinforced with Mesh for Hiatus Hernia: A Long-Term Follow-Up

To assess the recurrence of hiatal hernia five to ten years after repair using sutures versus sutures reinforced with non-absorbable mesh.

Randomized Controlled Trial of Laparoscopic Primary Crural Repair versus Primary Repair with Circular Bio-absorbable Hiatal Mesh Reinforcement in Hiatal Hernia Repair

To define the optimum laparoscopic hiatus hernia repair, ensuring long-term effect with minimal postoperative side effects.

Prevention of incisional hernias with prophylactic synthetic mesh placement during stoma reversal

The aim of this study is therefore to prospectively investigate whether prophylactic synthetic mesh placement reduces the rate of stomal site incisional hernias after stoma closure without increasing (infectious) complications.