60 results
Primary Objectives:- To evaluate and compare the overall survival (OS) of subjects with advanced or metastatic adenocarcinoma of the pancreas when treated with JAK 1/2 Inhibitor in combination with capecitabine versus capecitabine alone.Secondary…
To investigate feasibility, safety and toxicity as well as immune-response of an allogeneic tumor cell lysate (PheraLys) loaded onto autologous dendritic cells (MesoPher) in resected pancreatic cancer patients who received adjuvant standard of care…
This is a prospective phase II non-randomized single-center study in patients with LAPC. Patients are first treated with up to 8 cycles of FOLFIRINOX, followed by stereotactic radiotherapy for a total dose of 40 Gy in 5 fractions. Due to the known…
The objective of the study is to investigate the long-term clinical outcome of AIP with a minimum follow-up of two years.
The primary objective of this Phase 3 extension study will be to obtain essential long term safety data to augment the overall safety database. The secondary objective will be to augment the efficacy information collected in the double-blind study (…
Primary Objective: The proposed project involves a phase II study to investigate the feasibility and safety of radiofrequency ablation in irresectable locally advanced pancreatic cancer. Secondary Objectives: Secondary objectives of the study are…
Primary Objective:- To determine the incidence of EPI in pancreatic cancer.Secondary Objectives are: 1. To identify the predictive factors for the development of EPI in pancreatic cancer.2. To evaluate the occurrence of nutritional deficiencies in…
Primary Objective: - To investigate the efficacy of Namisol® after a single dose of Δ9-THC on the experienced pain intensity (measured by the VASpain in rest and on movement) in patients with chronic pancreatitis.Secondary Objectives:- To…
To assess the difference in efficacy of pancreatic enzymes in a self-dosage regimen after extensive patient-education in comparison to the standard treatment for patients with EPI.
Primary objectiveThe primary objective of this study is to assess the feasibility and safety of omitting prophylactic postoperative drainage after pancreatic surgery. This study was designed in order to gather conclusive information regarding the…
Primary objective: to investigate the safety of RFA in non-metastasized, irresectable locally advanced pancreatic cancer.Secondary objectives: to determine VAS pain score, length of hospital stay, survival, progression free survival and CA19-9…
Primary objective:- To investigate the analgesic efficacy of a stable dose treatment Namisol® in chronic pancreatitis patients suffering from abdominal pain. Analgesic efficacy is measured as mean difference in visual analogue scale (VAS) score (i.e…
To compare the outcome of early laparoscopic cholecystectomy (<72 hrs after randomization) with interval laparoscopic cholecystectomy (25-30 days after randomization) after mild biliary pancreatitis.
To analyze the incidence and course of EPI, before and after a PD for a (suspected) pancreatic or peri-ampullary (pre-)malignancy. Furthermore, the correlation between the presence of EPI and symptoms will be evaluated. In addition, the incidence of…
To analyze the incidence and course of EPI, before and after a PD for a suspected pancreatic or peri-ampullary malignancy. Furthermore, the effect of pancreatic enzyme supplementation on symptoms of EPI and the correlation of symptoms and abnormal…
Aim of this study is to investigate the natural course of early peripancreatic collections (i.e. acute fluid collections) in patients with predicted severe AP by CECT and by MRI.
To determine the reliability and feasibility of the Nanoduct sweat test system compared to the gold standard tests QPIT and Macroduct.
To determine the succes rate of the Nanoduct sweat test system.
A successfully conducted trial will have a positive impact on the future handling of thepancreatic remnant in distal pancreatectomy. The reliable and comparable data generated in this trial may support an evidence-based choice of a surgical…
The primary objective of this study is to establish the clinically relevance of extra protein supplementation on the height growth at children with Cystic Fibrosis. The secondary objectives of this study are to measure the effects of protein…