56 results
To investigate feasibility, safety and toxicity as well as immune-response of an allogeneic tumor cell lysate (PheraLys) loaded onto autologous dendritic cells (MesoPher) in resected pancreatic cancer patients who received adjuvant standard of care…
This is a prospective phase II non-randomized single-center study in patients with LAPC. Patients are first treated with up to 8 cycles of FOLFIRINOX, followed by stereotactic radiotherapy for a total dose of 40 Gy in 5 fractions. Due to the known…
The objective of the study is to investigate the long-term clinical outcome of AIP with a minimum follow-up of two years.
The primary objective of this Phase 3 extension study will be to obtain essential long term safety data to augment the overall safety database. The secondary objective will be to augment the efficacy information collected in the double-blind study (…
Primary Objective: The proposed project involves a phase II study to investigate the feasibility and safety of radiofrequency ablation in irresectable locally advanced pancreatic cancer. Secondary Objectives: Secondary objectives of the study are…
Primary Objective:- To determine the incidence of EPI in pancreatic cancer.Secondary Objectives are: 1. To identify the predictive factors for the development of EPI in pancreatic cancer.2. To evaluate the occurrence of nutritional deficiencies in…
To assess the difference in efficacy of pancreatic enzymes in a self-dosage regimen after extensive patient-education in comparison to the standard treatment for patients with EPI.
Primary objectiveThe primary objective of this study is to assess the feasibility and safety of omitting prophylactic postoperative drainage after pancreatic surgery. This study was designed in order to gather conclusive information regarding the…
Primary objective: to investigate the safety of RFA in non-metastasized, irresectable locally advanced pancreatic cancer.Secondary objectives: to determine VAS pain score, length of hospital stay, survival, progression free survival and CA19-9…
To compare the outcome of early laparoscopic cholecystectomy (<72 hrs after randomization) with interval laparoscopic cholecystectomy (25-30 days after randomization) after mild biliary pancreatitis.
To analyze the incidence and course of EPI, before and after a PD for a (suspected) pancreatic or peri-ampullary (pre-)malignancy. Furthermore, the correlation between the presence of EPI and symptoms will be evaluated. In addition, the incidence of…
To analyze the incidence and course of EPI, before and after a PD for a suspected pancreatic or peri-ampullary malignancy. Furthermore, the effect of pancreatic enzyme supplementation on symptoms of EPI and the correlation of symptoms and abnormal…
Aim of this study is to investigate the natural course of early peripancreatic collections (i.e. acute fluid collections) in patients with predicted severe AP by CECT and by MRI.
To determine the reliability and feasibility of the Nanoduct sweat test system compared to the gold standard tests QPIT and Macroduct.
To determine the succes rate of the Nanoduct sweat test system.
A successfully conducted trial will have a positive impact on the future handling of thepancreatic remnant in distal pancreatectomy. The reliable and comparable data generated in this trial may support an evidence-based choice of a surgical…
The primary objective of this study is to establish the clinically relevance of extra protein supplementation on the height growth at children with Cystic Fibrosis. The secondary objectives of this study are to measure the effects of protein…
The aim of the study is to compare the effect jejunal with that of gastric tube feeding on abdominal symptoms.
In this pilot-study we investigate the safety, feasibility and efficacy of IRE in locally advanced pancreatic carcinoma. We hypothesize that IRE of the pancreas is a safe treatment that will cause few complications. Moreover, we expect the treatment…
To determine the efficacy and safety of MEDI4736 evaluated as a single agent or in combination with tremelimumab in patients with metastatic pancreatic ductal adenocarcinoma (PDAC) whose disease has progressed on 5-FU-containing or gemcitabine-…