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Autoimmune Pancreatitis: Long-term Outcome

The objective of the study is to investigate the long-term clinical outcome of AIP with a minimum follow-up of two years.

NAtural history of Peri-pancreatic cOLlEctiONs in acute pancreatitis based on assessment of content with CECT and MRI.

Aim of this study is to investigate the natural course of early peripancreatic collections (i.e. acute fluid collections) in patients with predicted severe AP by CECT and by MRI.

The Nanoduct study: a new sweat test system tested

To determine the reliability and feasibility of the Nanoduct sweat test system compared to the gold standard tests QPIT and Macroduct.

Clinical evaluation of a new sweat test system in the diagnosis of cystic fibrosis after newborn screening

To determine the succes rate of the Nanoduct sweat test system.

Optimalisation of exocrine pancreatic insufficiency and pancreatic enzyme replacement therapy.

Primary aim of this study is to validate easy and reliable tests to detect EPI in patients after gastrointestinal surgery. The 72-hour faecal fat quantification (gold standard), will be compared with a shortened version of 24-hours, the FET and 13C-…

Epithelial Ion Transport Defects in Pancreatitis: establishment of an organoid model

Primary: To evaluate the ability to culture PDEC organoids from pancreatic duct biopsies. Secondary: (i) To evaluate ion transport in PDEC organoids derived from pancreatitis patients. (ii) To evaluate the ability of duodenal organoids to mimic ion…

18F-Prostate Specific Membrane Antigen PET-CT as a potential novel imaging modality for pancreatic cancer: A pilot study (PANSCAN-2)

To investigate the feasibility of using 18F-PSMA PET-CT as a tumor-specific molecular imaging in PC, thus allowing for improved detection, therapy selection, and therapy response assessment.

Prospective Multicenter Microbiota Study for Evaluation and Monitoring of Severe Acute Pancreatitis

1) To establish associations between microbiome profiles and disease severity in patients with acute pancreatitis. 2) To establish associations between specific microbial shifts and infectious complications in the subgroup of patients with…

Next generation sequencing in patients with pancreatic ductal adenocarcinoma (PAN-NGS).
A nationwide prospective, translational cohort study.

To determine the prevalence of actionable genetic alterations in PDAC patients <= 60 years old.

Preoperative detection of lymph node metastases in pancreatic and periampullary carcinoma using ultrasmall super paramagnetic iron oxide nanoparticle ferumoxtran-10.

The first objective is to improve preoperative staging with 3T NANO-MRI regarding the detection of lymph node metastases in patients with a pancreatic or periampullary carcinoma when compared to a conventional contrast-enhanced CT or MRI. Other…