24 results
What is the prevalence of gastro-intestinal disorders and which are the determinants?
The primary objective of the study is to compare gut permeability in metabolic healthier and metabolic unhealthier subjects by performing a MS permeability test. The secondary objectives are to study the correlation between gut permeability assessed…
A close correlation has been demonstrated between iron absorption and the capacity of gastric juice to release food iron. At high levels of gastric pH (>3,6), negligible amounts of non-haem iron would be released from dietary components and…
The aim of this study is to determine the immediate effects of oral alcohol consumption in healthy volunteers on gut wall integrity as measured by Intestinal Fatty Acid Binding Protein (I-FABP) and Lipopolysaccharide Binding Protein (LBP) These…
In this study the effect of the pneumoperitoneum on the intestine of children is objectified by measuring the iFABP levels in the urine, as an indicator for the ischemia or damage to the intestine. To exclude any iFABP increase due to intestinal…
The objective of this study is to determine if children with FAP demonstrate subliminal and supraliminal attentional biases to assumed activity of the abdomen compared to healthy children and if children with FAP interpret the assumed activity as…
To assess the relationship between postprandial symptoms and gastric emptying rate. The caloric intake and caloric gastric emptying rate in the pathogenesis of postprandial symptoms after sleeve gastrectomy will also be taken into account
Intestinal Permeability during Respiratory insufficiency in patients with acute exacerbation of COPD
The primary objective of the present study is to investigate if the intestinal permeability is increased in patients with an acute COPD exacerbation. To investigate this objective, the following research question have been formulated:- Is intestinal…
Gain insight into the mechanism underlying enhanced gastric mechanoperception and duodenal chemoperception, by comparing duodenal mRNA expression of genes and plasma and duodenal mucosal concentrations of proteins, involved in the chylomicron-apoA-…
To establish microcirculatory profiles using non-invasive diagnostic imaging in NEC.
Primary Objective: To assess the differences between lean and obese subjects in tissue PYY and GLP-1 levels and gene activity, and in L-cellular secretion before and directly after nutrient exposure. Secondary Objective: To correlate these…
Gain insight into the mechanism underlying enhanced mechanoperception of the stomach and duodenal chemoperception in response to fat in patients with functional dyspepsia.
Gain insight into the role of the duodenum in symptom generation in GERD at the mucosal level by comparing several components of the chylomicron-apoA-IV-CCK pathway between GERD patients and healthy subjects upon duodenal lipid load.
To study effects of AXOS (1) on gut health including among other parameters intestinal transit time, fecal cytotoxicity, pH, inflammatory markers, short-chain fatty acids and microbiota composition), gut permeability and gut functioning (bloating,…
In this small study we want to show that two sequential measurements of intestinal transit time by SITZMARK-method will provide strongly correlated results. In this way we hope to ascertain that regression to the mean did not play a role in the…
Primary objective is to evaluate and compare the glycaemic control in T2DM within the first year of LRYGB and LMBG. Secondary aim is to gain insight in the pathophysiological mechanisms that drive the conversion of malign to benign obesity.
(1) To assess parent-child attachment and interaction in a cohort of children and adolescents known with IF and (a history of) home PN dependence, and (2) to assess cognitive development and social-emotional functioning in these children.
To investigate the relationship between body composition and parenteral nutrition in children with intestinal failure at 6 months corrected age. The ultimate goil of this study is to optimize the treatment of children with intestinal failure by…
- to analyze the changes in the gut microbiome of IBD patients during pregnancy and try to find an association with disease activity - to analyze whether changes in the gut microbiome remain after post partum period of 3 months-to analyze gut…
*Evaluate whether patients who are discharged early and are continuously monitored recover just as safely at home as they do in the hospital.**Evaluate whether complications can be detected in a timely manner by using continuous vital signs and…