55 results
The objective of this study is to compare the efficacy of Infliximab-biosimilar to Infliximab-innovator and to demonstrate its noninferiority up to 30 weeks, in patients with ulcerative colitis or Crohn*s disease in remission under treatment with…
To assess the pharmacokinetics and safety of naloxegol in paediatric patients ages > 6 months to < 18 years receiving treatment with opioids.
The purpose of this current study is to evaluate the efficacy and safety of the 3-day oral aprepitant regimen when administered concomitantly with ondansetron, with or without dexamethasone, in pediatric patients, from 6 months to 17 years of age,…
The main objectives of this study are to evaluate the performance and ease of use of the Follow me mode of the AutoLap system during general and gynecological laparoscopic procedures.Study Procedures: No. & type. A total of 35 laparoscopic…
To define the optimum laparoscopic hiatus hernia repair, ensuring long-term effect with minimal postoperative side effects.
To evaluate the hypothesis that patients with an abnormal pancreatic duct (PD) in which the transluminal stents are left in situ have a lower pancreatic fluid collection recurrence rate after endoscopic transluminal drainage in comparison to…
The primary objective of this study is to compare a semi-mechanical with a hand sewn cervical anastomosis after esophagectomy with gastric tube reconstruction for cancer.
Primary objectiveTo determine the effect of multiple dose OME on the pharmacokinetics (AUC0-8h, Cmax, C8h) of BOC.Secondary objectives:To determine the effect of steady state BOC on the pharmacokinetics (AUC0-8h, Cmax, C8h) of multiple dose OME.To…
The primary aim of this feasibility study is to determine the quality of bowel cleansing in patients undergoing colonoscopy with the ClearPath system after modified bowel preparation.
The primary aim of the study is to determine the effect of orally administered AZD2516 as a reduction of the number of reflux episodes, in comparison with placebo, over a period of approximately three hours after a meal, in healthy male volunteers.
Primary:to examine the effect of co-administration with omeprazole on the pharmacokinetics of SSP-002358.Secondary:to provide additional safety information for SSP-002358 when administered alone or in combination with omeprazole.
To study in healthy human volunteers safety of the iPill system. Secondary objectives are recording of pH and temperature of the gastrointestinal tract. To investigate the measurement and communication functionality of the iPill system
The purpose of the study is to evaluate the safety and effectiveness of the LINX device in the treatment of GERD
Study effectiveness and PK of rectal omeprazole compared to oral omeprazole
To perform a human pilot study to prove the hypothesis that a hybrid transgastric cholecystectomy is a safe procedure.
Primary To evaluate the treatment effect of pasireotide s.c. on plasma glucose levels during GTT at the end of s.c. dose escalation phase.Secondary: Pulse rate, hematocrit, insulin, glucagon, GLP-1 and GIP secretion during GTT at the end of s.c.…
To define the optimum laparoscopic anti-reflux operation, ensuring long-term reflux control with minimal postoperative dysphagia and gas-related symptoms.
Objectives: The purpose of this study is to establish the safety of the product.This study is designed to evaluate the safety of the device in protecting the anastomotic junction created during a stoma reversal procedure. The objectives of this…
The goal of the current study is to investigate the correlation of IntelliCap generated environmental information (gastrointestinal pH and temperature) with an established nuclear imaging technique. In addition, the functionality of the IntelliCap…
To determine if PHA-739358 has an antitumor activity against breast, ovaria, pancreatic, colerectal, small and non small cell squamous lung cancer.