78 results
The objective of this study is to compare the efficacy of Infliximab-biosimilar to Infliximab-innovator and to demonstrate its noninferiority up to 30 weeks, in patients with ulcerative colitis or Crohn*s disease in remission under treatment with…
What is the prevalence of gastro-intestinal disorders and which are the determinants?
To assess the pharmacokinetics and safety of naloxegol in paediatric patients ages > 6 months to < 18 years receiving treatment with opioids.
The primary objective of the study is to compare gut permeability in metabolic healthier and metabolic unhealthier subjects by performing a MS permeability test. The secondary objectives are to study the correlation between gut permeability assessed…
The purpose of this current study is to evaluate the efficacy and safety of the 3-day oral aprepitant regimen when administered concomitantly with ondansetron, with or without dexamethasone, in pediatric patients, from 6 months to 17 years of age,…
The main objectives of this study are to evaluate the performance and ease of use of the Follow me mode of the AutoLap system during general and gynecological laparoscopic procedures.Study Procedures: No. & type. A total of 35 laparoscopic…
To define the optimum laparoscopic hiatus hernia repair, ensuring long-term effect with minimal postoperative side effects.
To evaluate the hypothesis that patients with an abnormal pancreatic duct (PD) in which the transluminal stents are left in situ have a lower pancreatic fluid collection recurrence rate after endoscopic transluminal drainage in comparison to…
A close correlation has been demonstrated between iron absorption and the capacity of gastric juice to release food iron. At high levels of gastric pH (>3,6), negligible amounts of non-haem iron would be released from dietary components and…
The primary objective of this study is to compare a semi-mechanical with a hand sewn cervical anastomosis after esophagectomy with gastric tube reconstruction for cancer.
Primary objectiveTo determine the effect of multiple dose OME on the pharmacokinetics (AUC0-8h, Cmax, C8h) of BOC.Secondary objectives:To determine the effect of steady state BOC on the pharmacokinetics (AUC0-8h, Cmax, C8h) of multiple dose OME.To…
The aim of this study is to determine the immediate effects of oral alcohol consumption in healthy volunteers on gut wall integrity as measured by Intestinal Fatty Acid Binding Protein (I-FABP) and Lipopolysaccharide Binding Protein (LBP) These…
In this study the effect of the pneumoperitoneum on the intestine of children is objectified by measuring the iFABP levels in the urine, as an indicator for the ischemia or damage to the intestine. To exclude any iFABP increase due to intestinal…
The primary aim of this feasibility study is to determine the quality of bowel cleansing in patients undergoing colonoscopy with the ClearPath system after modified bowel preparation.
The objective of this study is to determine if children with FAP demonstrate subliminal and supraliminal attentional biases to assumed activity of the abdomen compared to healthy children and if children with FAP interpret the assumed activity as…
The primary aim of the study is to determine the effect of orally administered AZD2516 as a reduction of the number of reflux episodes, in comparison with placebo, over a period of approximately three hours after a meal, in healthy male volunteers.
Primary:to examine the effect of co-administration with omeprazole on the pharmacokinetics of SSP-002358.Secondary:to provide additional safety information for SSP-002358 when administered alone or in combination with omeprazole.
To study in healthy human volunteers safety of the iPill system. Secondary objectives are recording of pH and temperature of the gastrointestinal tract. To investigate the measurement and communication functionality of the iPill system
The purpose of the study is to evaluate the safety and effectiveness of the LINX device in the treatment of GERD
To assess the relationship between postprandial symptoms and gastric emptying rate. The caloric intake and caloric gastric emptying rate in the pathogenesis of postprandial symptoms after sleeve gastrectomy will also be taken into account