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A randomised, open-label clinical trial assessing the efficacy of octreotide to decrease iron infusion and blood transfusion requirements in patients with refractory anaemia due to gastrointestinal bleeding from angiodysplasias.

To assess the efficacy of octreotide in decreasing the need for iron infusions or blood transfusions in patients with refractory gastrointestinal bleedings due to small bowel angiodysplasias despite endoscopic intervention.

An uncontrolled, pilot-study assessing the efficacy of octreotide LAR to decrease transfusion requirements and endoscopy frequency in patients with Rendu-Osler-Weber and gastrointestinal bleeding

To assess the efficacy of octreotide LAR in decreasing the need for transfusions and endoscopic intervention in patients ROW with refractory anaemia due to gastrointestinal bleeding telangiectasias.

Clinical Evaluation of Hemospray: Hemostasis of Active GI Lumincal Tract Bleeding (HALT)

The goal of this investigation is to show that Hemospray is effective in achieving initial hemostasis rates equivalent to standard of care treatment and a decreased rate of further bleed when compared to standard of care up to 72 hours after…

A prospective Evaluation of the Torax Medical Inc. Magnetic Esophageal Sphincter for the treatment of Gastroesophageal Reflux Disease (GERD).

This study is conducted to evaluate a novel method of augmenting a weak Lower Esophageal Sphincter (LES) with a magnetic esophgeal sphincter device.

Urgent versus elective colonoscopy in acute lower gastrointestinal bleeding:
a randomized controlled trial

To examine differences in hospital length of stay (LOS) in patients with acute LGIB receiving either urgent colonoscopy or standard elective colonoscopy.

Effectiveness of Somatostatin Analogues in patients with Gastric antral
vascular ectasia and symptomatic gastrointestinal bleeding: SAGAVE-trial

Primary Objective: To investigate the efficacy and safety of octreotide treatment (a somatostatin analogue) in decreasing the transfusion requirements (IV iron infusions and / or red blood cell transfusions) in patients with GI bleeding caused by…

A multi-center randomized controlled study of primary prevention of esophageal variceal bleeding in cirrhotic patients treated with HVPG-guided beta- blocker therapy or standard heart rate-guided beta-blocker therapy.

To determine cost-effectiveness of hepatic venous pressure gradient (HVPG)-guided nonselective beta-blocker therapy as compared to standard heart rate-guided beta-blocker therapy in the primary prevention of esophageal variceal bleeding in cirrhotic…

Medication (de)prescribing in hospitalized geriatric patients with sarcopenia, less is more?

The effects of DPA compared to STOPP-START approach (SSA) prescribing on adverse drug reactions, medical complications, hospital readmission, quality of life in hospitalized geriatric patients with sarcopenia

Dabigatran trough levels in elderly patients: are these increased, and to what extent? A pilot study.

Objective of the study is to measure dabigatran trough levels, percentage of dabigatran glucuronidation, and diluted thrombin time, to test whether these levels are different in elderly patients.