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A study proposal to investigate the sequels of mucosal inflammation caused by ETEC infection- the effects of probiotics

The main objective of this study is to investigate the effect of probiotics on the sequels of ETEC administration as intestinal permeability, inflammation and clinical signs as total faecal output, relative faecal dry weight and mucin excretion in…

Establishing colonisation with non-toxigenic Clostridioides difficile in healthy volunteers.

Primary objective:- To evaluate the safety and tolerability of colonisation with non-toxigenic C. difficile.- To establish the effective protocol to obtain colonisation with non-toxigenic C. difficile in the majority of subjects.Secondary objective…